Organ Systems
Organ Systems - Related Videos
13:16
A Whole Cell Bioreporter Approach to Assess Transport and Bioavailability of Organic Contaminants in Water Unsaturated Systems
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Cited by 5 •
2014
A whole cell bioreporter assay with Burkholderia sartisoli RP037-mChe was developed to detect fractions of an organic contaminant (i.e., fluorene) available for bacterial degradation after active transport by mycelia bridging air-filled pores in a water unsaturated model system.
13:19
The Use of Chemostats in Microbial Systems Biology
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Cited by 67 •
2013
Cell growth rate is a regulated process and a primary determinant of cell physiology. Continuous culturing using chemostats enables extrinsic control of cell growth rate by nutrient limitation facilitating the study of molecular networks that control cell growth and how those networks evolve to optimize cell growth.
05:46
High-pressure Sapphire Cell for Phase Equilibria Measurements of CO2/Organic/Water Systems
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2014
The high pressure sapphire cell apparatus is a unique tool to study, without sampling, phase behavior under a wide range of pressures. Using a cathetometer, very precise volume measurements can be recorded to measure liquid expansion and phase composition. Thus, this synthetic method enables the study of (1) phase equilibria of multi-component mixtures and (2) the partition behavior of catalyst or model compounds as a function of pressure.
01:32
Three-Dimensional Culture Systems: Spheroids and Organoids
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2026
Three-dimensional (3D) culture systems, including spheroids and organoids, support New Approach Methodology (NAM)-aligned research by providing more physiologically relevant models than conventional two-dimensional cell cultures. Because they more closely resemble the structure and cellular interactions of tissues and organs, these systems can provide physiologically relevant data before advancing to animal studies. Spheroids as Disease and Drug Screening Models Spheroids are generated when one...
01:35
Organ-on-Chip Models
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2026
Introduction to Organ-on-Chip Models Organ-on-chip models are advanced microphysiological systems that recreate key structural and functional features of human organs in a controlled laboratory setting. These devices integrate living human cells within microfluidic channels, allowing researchers to simulate tissue–tissue interfaces, fluid flow, and mechanical forces that are essential for normal organ function. Unlike traditional cell cultures, which often lack these dynamic physiological cues,...
FAQs
Coordination depends on several communication routes operating together. Nerve impulses provide rapid signaling, chemical signals regulate activities, and circulation helps connect distant organs within the organism. These mechanisms allow specialized tissues and organs to respond as a coordinated network rather than as isolated structures, supporting integrated body functions and helping maintain internal balance.
Feedback mechanisms, especially those associated with homeostasis, help keep internal conditions within ranges compatible with survival and growth. They link changes in the body to regulatory responses, allowing system activity to be adjusted rather than remaining fixed. Studying these responses helps biologists explain how organisms preserve internal balance despite ongoing physiological or environmental change.
Organ systems connect multiple levels of organization, from specialized tissues and individual organs to coordinated physiological networks. Examining these relationships shows how a change or activity at one level can contribute to broader body functions. This systems perspective is important because biological outcomes often depend on interactions among components rather than on the action of one organ alone.
The nervous and endocrine systems provide complementary forms of coordination within the body. Nerve impulses support signaling, while chemical signals contribute to regulation across organ systems. Considering both routes helps explain how body functions are synchronized and how researchers analyze communication, control, and feedback when studying normal physiology, disease, or responses to environmental change.
Biologists examine how organs, tissues, signals, and feedback mechanisms operate together under normal conditions and how those relationships change in disease. This approach moves beyond analyzing a single structure and considers broader physiological networks. The resulting understanding can support medical research and inform diagnostics or treatments directed at organs and the systems in which they function.
A systems perspective recognizes that targeting one organ may influence connected physiological networks. For this reason, medical research considers both individual organs and their wider interactions when investigating health, disease, diagnostics, and treatment. The approach can also clarify why understanding communication and coordination across systems is relevant to evaluating complex biological conditions.