Sitting Drop
Sitting Drop - Related Videos
08:24
Sit-to-stand-and-walk from 120% Knee Height: A Novel Approach to Assess Dynamic Postural Control Independent of Lead-limb
0 Views •
Cited by 5 •
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Here, we present a novel protocol to measure positional stability at key events during the sit-to-stand-to-walk using the center-of-pressure to the whole-body-center-of-mass distance. This was derived from the force platform and three-dimensional motion-capture technology. The paradigm is reliable and can be utilized for the assessment of neurologically compromised individuals.
09:20
Picoinjection of Microfluidic Drops Without Metal Electrodes
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Cited by 2 •
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We have developed a technique for picoinjecting microfluidic drops that does not require metal electrodes. As such, devices incorporating our technique are simpler to fabricate and to use.
01:13
Excess Pressure Inside a Drop and a Bubble
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2023
The shape of a small drop of liquid can be considered spherical, neglecting the effect of gravity. This drop can further be considered as two equal hemispherical drops put together due to surface tension. The forces acting on the spherical drop are due to the pressure of the liquid inside the drop, the pressure due to air outside the drop, and the force due to the surface tension acting on the two hemispherical drops. where γ corresponds to the surface tension. Recalling that the force per...
01:46
Developing Neuron Balls Using a Hanging Drop Culture Technique
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2025
This video demonstrates the process of generating neuron balls using a hanging drop culture technique. Within the hanging drops, cells move towards the bottom, self-assembled into three-dimensional structures forming neuron balls, which can be used for neurobiological studies.
21:16
An In Vitro Skin Irritation Test (SIT) using the EpiDerm Reconstructed Human Epidermal (RHE) Model
0 Views •
Cited by 57 •
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In this video, we demonstrate the EpiDerm Skin Irritation test (EpiDerm SIT) developed and validated for in vitro skin irritation testing of chemicals, including cosmetic and pharmaceutical ingredients.
FAQs
Examine whether movement persists in a consistent direction and produces overall displacement. True motility reflects activity associated with cellular structures such as flagella, whereas Brownian motion appears random and vibration-like, with no net movement. Using these criteria during microscopy helps distinguish active biological movement from passive motion in the surrounding liquid and supports more reliable preliminary observations.
Flagella can contribute to the sustained, directional movement used to recognize true motility. In a Sitting drop, observing movement directly under magnification connects the visible behavior with a cellular structure rather than treating every change in position as equivalent. This makes the technique useful for examining movement-related biological processes in living microorganisms.
Because the specimen remains unstained and in a liquid environment, observers can examine living cells or microorganisms directly. That setting is important when the aim is to assess movement, behavior, or viability. The method therefore preserves observations of organisms in conditions closer to their immediate surroundings, rather than altering the observation through a staining step.
Place a drop of liquid containing living cells or microorganisms on a microscope slide, position a coverslip over the drop, and examine the specimen under magnification. The preparation keeps the liquid and organisms available for direct viewing. This straightforward workflow makes rapid observation possible without requiring a staining step.
Observations can reveal whether microorganisms display true motility or Brownian motion during examination. The same preparation can also support assessments of cell behavior and viability. These outcomes make the technique useful for rapid screening before more detailed investigation and for preliminary identification in biology, particularly when movement provides a relevant observable characteristic.
It is especially useful when a researcher needs a rapid, uncomplicated view of living microorganisms or cells. Biology teaching can use it to demonstrate the difference between active motility and Brownian motion, while preliminary identification can use movement as an observable characteristic. It also supports investigations of cell behavior, viability, and movement-related biological processes.