Multi-channel Pipette
Multi-channel Pipette - Related Videos
09:45
Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow
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Cited by 8 •
2011
Dielectrophoresis (DEP) is an effective method to manipulate cells. Printed circuit boards (PCB) can provide inexpensive, reusable and effective electrodes for contact-free cell manipulation within microfluidic devices. By combining PDMS-based microfluidic channels with coverslips on PCBs, we demonstrate bead and cell manipulation and separation within multichannel microfluidic devices.
05:30
Making Patch-pipettes and Sharp Electrodes with a Programmable Puller
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Cited by 22 •
2008
This video shows how to use a programmable puller to make patch pipettes and sharp electrodes for electrophysiology. The same procedure can be used to make a variety of glass tools, including injection needles.
06:35
Introduction to Serological Pipettes and Pipettors
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2023
The serological pipette is frequently used in the laboratory for transferring milliliter volumes of liquid, from less than 1 ml to up to 50 ml. The pipettes can be sterile, plastic, and disposable or sterilizable, glass and reusable. Both kinds of pipettes use a pipet-aid, for the aspiration and dispensation of liquids. Different sizes of pipettes can be used with the same pipet-aid for a variety of experimental assays. For example, serological pipettes are useful for mixing chemical solutions...
05:42
Measurement of Ion Concentration in the Unstirred Boundary Layer with Open Patch-Clamp Pipette: Implications in Control of Ion Channels by Fluid Flow
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Cited by 2 •
2019
Mechanosensitive ion channels are often studied in terms of fluid flow/shear force sensitivity with patch-clamp recording. However, depending on the experimental protocol, the outcome on fluid flow-regulations of ion channels can be erroneous. Here, we provide methods for preventing and correcting such errors with a theoretical basis.
05:12
Pressure-polishing Pipettes for Improved Patch-clamp Recording
0 Views •
Cited by 13 •
2008
This is a guide to modifying the shape of glass micropipettes. Specifically, by using heat and air pressure the taper is widened without increasing the tip opening, leading to lower pipette resistance. This is critical to obtain low noise recordings of small cells but is useful in many applications.
FAQs
Its aligned channels maintain the same spatial arrangement as the wells or tubes being processed. Each tip draws liquid from one position and dispenses it into the corresponding position in another row or column. This parallel alignment helps researchers handle multiple samples or conditions consistently without losing track of their intended locations during plate-based experiments.
Defined volumes establish a consistent amount for each transfer, while individual tips keep the channels separated during aspiration and dispensing. Together, these features support parallel sample handling across multiple wells or tubes. In assays with many specimens or conditions, consistent transfers help limit variation introduced by repetitive manual liquid handling.
The main difference is parallel operation. Instead of transferring liquid one well or tube at a time, several corresponding positions can be handled during the same aspiration and dispensing sequence. This reduces repeated manual actions, improves processing speed, and supports greater consistency when an experiment requires many similar transfers across a plate.
A typical workflow aligns the channels with the selected wells or tubes, aspirates a defined volume, and dispenses it into the corresponding receiving positions. The same parallel relationship is maintained throughout the transfer. This approach is useful when samples, reagents, or dilution steps must be distributed consistently across rows or columns.
Applications supported by this approach include ELISA workflows, serial dilutions, cell-based assays, and reagent distribution for diagnostic testing. These experiments often require repeated transfers across many wells or conditions. Parallel handling helps process those layouts efficiently while preserving the correspondence between samples, reagents, and assay positions.
It is particularly useful when a procedure contains many repeated transfers involving multiple specimens or experimental conditions. In immunology and infection research, that may include distributing reagents for diagnostic testing or preparing serial dilutions. The resulting workflow can increase throughput, standardize sample handling, and reduce variation from repetitive manual pipetting.