Drill-hole Defect

A drill-hole defect is a localized opening in bone, most commonly the skull, created when a surgical drill or similar instrument penetrates and removes part of the cortex. On radiographic imaging, it appears as a round or oval area of reduced bone density, with its appearance influenced by the hole’s size, location, surgical purpose, and stage of healing. In medicine, recognizing this pattern helps clinicians distinguish an expected postoperative finding from traumatic fracture, infection, or other destructive lesions. Interpretation combines imaging features with the patient’s surgical history and symptoms, supporting neurosurgical follow-up, treatment planning, and accurate clinical documentation.

Drill-hole Defect - Related Videos

Research

JoVE EoE - Large Animal Models

Generating a Rabbit Calvarial Defect Model: A Surgical Procedure to Create Round Defects in the Top Portion of the Rabbit Skull to Assess Bone Substitute Materials for Bone Regeneration Capacities

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2025

In this video, we describe the surgical procedure to generate a rabbit calvarial model to evaluate the bone regeneration capacities of bone sample substitution materials of interest.

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models

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Cited by 19 •

2014

One constraint of preclinical research in the field of bone repair is the lack of experimental control over the local mechanical environment within a healing bone lesion. We report the design and use of an external fixator for bone repair with the ability to change fixator stiffness in vivo.

Research

JoVE Journal - Medicine
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Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

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Cited by 12 •

2016

Although mouse models are invaluable tools for bone tissue engineering, models of long bone defects are sparse. This need motivated development of the present protocol which uses a locking plate with four screws and a dedicated jig to perform and stabilize a reproducible, femoral, critical-size defect with low morbidity.

Coronoid-Temporalis Pedicled Flap for Orbital Floor Defect Reconstruction

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2025

This protocol presents a novel coronoid-temporalis pedicled flap (CTPF) technique for reconstructing small-to-medium orbital floor defects. CTPF avoids microvascular risks while maintaining biomechanical stability. Clinical cases demonstrate effective structural restoration, reduced complications, and preserved facial symmetry, offering a viable alternative to traditional grafts or alloplastic materials.

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

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Cited by 32 •

2013

An experimental technique for the treatment of osteochondral defects in the rabbit's knee joint is described. The implantation of allogeneic mesenchymal stem cells into osteochondral defects provides a promising development in the field of tissue engineering. The preparation of fibrin-cell-clots in vitro offers a standardized method for implantation.

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