Noninvasive Ultrasound
Noninvasive Ultrasound - Related Videos
09:31
Noninvasive Blood Pressure Measurement Techniques
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2023
Source: Hamna J. Qureshi and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana Here we will highlight the key similarities and differences of noninvasive blood pressure measurement techniques between humans and rodents and examine the engineering principles that govern blood pressure. The principles that govern current cuff technology to acquire systolic and diastolic pressures will also be discussed. Commercially available cuffs that connect...
14:20
High-frequency Ultrasound Imaging of the Abdominal Aorta
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2023
Source: Amelia R. Adelsperger, Evan H. Phillips, and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana High-frequency ultrasound systems are used to acquire high resolution images. Here, the use of a state-of-the-art system will be demonstrated to image the morphology and hemodynamics of small pulsatile arteries and veins found in mice and rats. Ultrasound is a relatively inexpensive, portable, and versatile method for the noninvasive...
06:45
Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke
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Cited by 4 •
2023
This work demonstrates the use of a multimodal ultrasound-based imaging platform for noninvasive imaging of ischemic stroke. This system allows for the quantification of blood oxygenation through photoacoustic imaging and impaired perfusion in the brain through acoustic angiography.
02:37
Ophthalmic Drug Delivery for Noninvasive Neuromodulation in a Mouse Model
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2025
Source: Zhan, J., et al. Non-invasive Strategies for Chronic Manipulation of DREADD-controlled Neuronal Activity. J. Vis. Exp. (2019)This video demonstrates a non-invasive ophthalmic drug delivery method for targeted neuromodulation. The drug is delivered via eye drops, absorbed into the circulation, crosses the blood-brain barrier, and activates specific neuronal receptors.
08:01
In utero Measurement of Heart Rate in Mouse by Noninvasive M-mode Echocardiography
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Cited by 5 •
2013
Ultra-high frequency ultrasound is a powerful live imaging tool to examine cardiac abnormalities in small animals. Its noninvasiveness allows maintaining the physiologic state of embryos. Herein, we show the use of M-mode ultrasound to measure the heart rates of embryos at E18.5 in utero.
FAQs
Acoustic impedance differences determine how tissues interact with the transmitted sound pulses. As echoes return to the transducer, variations in those echoes make internal structures appear differently in the resulting image. This contrast allows clinicians to distinguish organs and tissues during examination without relying on ionizing radiation or an incision.
Doppler processing analyzes changes associated with moving blood rather than only displaying stationary anatomy. This enables ultrasound to provide information about blood flow during cardiovascular assessment and other examinations where movement is clinically relevant. Combining structural images with blood-flow information helps clinicians evaluate anatomy and circulation during the same real-time study.
Portability allows ultrasound to be used in point-of-care care, bringing imaging closer to the patient and clinical decision. Real-time imaging lets clinicians observe anatomy as the examination occurs rather than relying only on previously collected images. Together, these features support diagnosis, cardiovascular assessment, pregnancy monitoring, and procedure guidance.
During needle placement, ultrasound provides real-time visualization that can guide the procedure while the clinician works. The transducer sends sound pulses and converts returning echoes into an image, allowing relevant internal structures to be viewed during the intervention. This application extends ultrasound beyond diagnosis to procedural support without requiring an incision for imaging.
Clinical uses include general diagnosis, pregnancy monitoring, cardiovascular assessment, and point-of-care care. These applications take advantage of ultrasound’s ability to visualize internal organs and tissues, assess blood flow through Doppler processing, and provide images during procedures. Its favorable safety profile also supports repeated examinations when ongoing assessment is needed.
Three-dimensional imaging and elastography represent advances that broaden ultrasound beyond its established imaging applications. The overview identifies both technologies as expanding clinical and research uses, building on ultrasound’s existing ability to provide real-time information without ionizing radiation. Their continued development supports investigation of additional ways to assess tissues and internal anatomy.