Surgical Lesion
Surgical Lesion - Related Videos
08:16
Comparative Lesions Analysis Through a Targeted Sequencing Approach
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2019
This article describes a method to identify clonal and subclonal alterations among different specimens from a given patient. Although the experiments described here focus on a specific tumor type, the approach is broadly applicable to other solid tumors.
12:45
Stereotaxic Surgery for Excitotoxic Lesion of Specific Brain Areas in the Adult Rat
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Cited by 22 •
2012
Targeted ablation of specific brain region(s) by infusion of an excitotoxin using stereotaxic coordinates is described. This technique could also be adapted for infusion of other chemicals into the rat brain.
09:22
Sectioning Mammary Gland Whole Mounts for Lesion Identification
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Cited by 13 •
2017
We developed a method to successfully remove, process, section, and stain, for histopathological evaluation, mammary tissue that had originally been fixed on slides as whole mounts. This method may promote the collection and evaluation of mammary gland whole mounts in reproductive and developmental test guideline studies.
10:09
Development of a Unilaterally-lesioned 6-OHDA Mouse Model of Parkinson's Disease
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Cited by 121 •
2012
A protocol for performing unilateral 6-OHDA lesions of the medial forebrain bundle in mice is described. This method has a low mortality rate (13.3 %) with 89% of the surviving animals showing >95% loss of striatal dopamine and 90.63±-4.02 % ipsiversive rotational bias towards the side of the lesion.
03:34
Laparoscopic Duodenum-Preserving Pancreatic Head Resection via Inferior Infracolic Approach: A Surgical Approach for Benign Lesions
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2024
This article provides a whole technical process of laparoscopic duodenum-preserving pancreatic head resection via an inferior infracolic approach. This is a surgical approach for benign tumors without intraoperative fluorescence image guidance.
FAQs
These factors help determine whether operative evaluation, biopsy, removal, or repair is appropriate. A lesion causing symptoms may require intervention for relief, while an abnormal appearance or concerning location may justify tissue assessment or removal. The possibility of harm also affects urgency and the extent of treatment, linking the surgical plan to both immediate problems and future complications.
Histopathological analysis examines a submitted specimen to characterize the abnormal tissue and support diagnosis. It can help distinguish benign from malignant disease when that distinction is clinically relevant. This information may clarify whether the operative treatment addressed the underlying problem and can guide subsequent medical decisions based on the tissue findings.
Separating abnormal tissue from viable structures balances treatment effectiveness with preservation of functioning tissue. Excision can remove tissue responsible for symptoms or potential harm, but unnecessary damage may interfere with repair or recovery. This principle is especially important when the lesion lies near structures that must remain intact for the affected area to function properly.
The procedure begins by exposing the affected area so the lesion and nearby tissue can be assessed directly. The surgeon then separates or excises diseased tissue while preserving viable structures, controls bleeding, and may send a specimen for histopathological analysis. Depending on the problem, the operation may focus on evaluation, biopsy, removal, repair, or a combination of these goals.
Operative management may be considered when symptoms, appearance, location, or potential harm make further action necessary. Biopsy supports tissue diagnosis, removal addresses abnormal or damaging tissue, and repair restores an area that has been wounded or damaged. The selected approach depends on the lesion’s clinical features and whether the main need is diagnosis, symptom relief, prevention, or definitive treatment.
Treatment can provide several outcomes, including a clearer diagnosis through tissue analysis, relief of symptoms, prevention of complications, and definitive treatment when benign or malignant disease is identified. Examination and imaging help locate or characterize the problem, while operative findings and specimen analysis add information that supports clinical assessment and further management.