Tumor Margin Mapping

Tumor margin mapping is a clinical and surgical method for identifying the boundaries of a tumor and its relationship to surrounding healthy tissue, helping guide treatment decisions. It combines spatial information from medical imaging, operative visualization, and, when appropriate, tissue sampling to mark tumor extent and assess whether disease approaches or remains within a planned resection margin. In medicine, this approach supports more precise surgery, helps clinicians evaluate residual disease risk, and can improve communication between radiologists, surgeons, and pathologists. Accurate margin assessment is particularly important when tumors infiltrate nearby structures or when preserving functional tissue is a priority.

Tumor Margin Mapping - Related Videos

Research

JoVE Journal - Medicine

Enhanced Communication of Tumor Margins Using 3D Scanning and Mapping

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Cited by 9 •

2023

A novel method for 3D scanning and virtual mapping of cancer resections is proposed with the goal of improving communication among the multidisciplinary cancer care team.

Research

JoVE Journal - Medicine
Free Sample

Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence

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Cited by 27 •

2011

Here we describe a method to quantify molecular heterogeneity in histological sections of tumor material using quantitative immunofluorescence, image analysis, and a statistical measure of heterogeneity. The method is intended for use in clinical biomarker development and analysis.

Selective Harvesting of Marginating-pulmonary Leukocytes

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Cited by 1 •

2016

Marginating-pulmonary leukocytes exhibit unique characteristics and distinct immunological functions compared to other leukocyte populations. Here we describe selective harvesting of this subpopulation of pulmonary leukocytes, by forced perfusion of the lungs in rats and mice. Marginating-pulmonary leukocytes seem critical in determining susceptibility to blood-borne and lung-related diseases.

Education

JoVE Business - Marketing

Margins and Profits Margins II

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2025

Financial metrics are essential for understanding a company's performance, helping businesses achieve profitability, and monitoring financial progress. These metrics guide sales targets, cost structures, and marketing effectiveness decisions. Setting target revenues ensures sales cover operating expenses and generate profits. For example, a business planning expansion might set higher sales targets to cover increased operational costs while maintaining profitability. The target revenue is a...

Margins and Profits Margins I

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2024

Margins and profit metrics are crucial for businesses to evaluate their profitability and cost management. By comparing sales revenue to various costs, these metrics help companies make informed decisions about pricing and overall financial strategy. Gross margin represents a company's profit after covering the direct production costs. It highlights the efficiency of managing production. A higher gross margin means the company effectively converts sales into earnings after accounting for the...

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