Non-invasive Vascular Imaging
Non-invasive Vascular Imaging - Related Videos
07:31
Testing the Vascular Invasive Ability of Cancer Cells in Zebrafish (Danio Rerio)
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Cited by 19 •
2016
This method utilizes zebrafish embryos to efficiently test the vascular invasive ability of cancer cells. Fluorescent cancer cells are injected into the precardiac sinus or yolk sac of developing embryos. Cancer cell vascular invasion and extravasation is assessed via fluorescence microscopy of the tail region 24 to 96 hr later.
12:00
Non-invasive Parenchymal, Vascular and Metabolic High-frequency Ultrasound and Photoacoustic Rat Deep Brain Imaging
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Cited by 9 •
2015
The present work describes a new protocol to perform non-invasive high-frequency ultrasound and photoacoustic based imaging on rat brain, to efficiently visualize deep subcortical regions and their vascular patterns by directing signals on skull foramina naturally present on animal cranium.
09:33
A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
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Cited by 16 •
2015
The present article describes the methodological considerations for several non-invasive assessments of vascular function and morphology that are commonly used in medical research to assess different stages of atherosclerosis.
08:05
Doppler Ultrasonography for Live Imaging and Quantification of Ovarian Vascular Function in Mice
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Cited by 1 •
2025
Changes in ovarian blood flow during the preovulatory period are essential for ovulation. Doppler ultrasonography has been used in humans and large animals to assess ovarian hemodynamics and perfusion. A protocol is presented for applying Doppler ultrasonography to evaluate ovarian hemodynamics during the preovulatory and periovulatory phases in mice.
09:52
Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
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Cited by 25 •
2013
Recently developed imaging techniques using near-infrared fluorescence (NIRF) may help elucidate the role the lymphatic system plays in cancer metastasis, immune response, wound repair, and other lymphatic-associated diseases.
FAQs
Doppler ultrasound estimates blood motion from changes in reflected sound waves. The measured signal links moving blood to changes in the returned waveform, allowing investigators to assess flow-related behavior without inserting a catheter. In neuroscience, this makes the technique useful for examining vascular dynamics alongside questions about circulation and brain function.
Magnetic resonance imaging uses magnetic fields and radiofrequency signals to map vessel anatomy and blood-flow patterns. This combination allows researchers to examine both the structural arrangement of cerebral vessels and associated circulation. It therefore complements motion-based flow measurements by providing a broader view of vascular organization and perfusion-related patterns in the brain.
Neurovascular coupling describes the relationship between neural activity and vascular responses, while perfusion concerns blood delivery through tissue. Imaging these features helps researchers study how brain circulation supports nervous-system function. Their assessment can also reveal vascular changes associated with stroke, tumors, and neurodegenerative disease, linking vessel behavior with neurological processes.
The two approaches emphasize different measurements. Doppler ultrasound detects motion-dependent changes in reflected sound waves, making flow-related behavior central to its readout. Magnetic resonance imaging uses magnetic fields and radiofrequency signals to map vessel anatomy and blood-flow patterns. Comparing their outputs can give neuroscience studies complementary information about circulation and vascular structure.
Researchers can characterize cerebrovascular structure, neurovascular coupling, perfusion, and abnormal vascular patterns in conditions such as stroke, tumors, and neurodegenerative disease. These measurements connect imaging findings with disease-associated changes in brain circulation. The approach supports investigation of both vascular abnormalities and their relevance to neurological research without requiring catheter insertion.
Because these methods do not require surgical intervention, researchers can repeat vascular assessments during longitudinal studies. Repeated measurements help track changes in cerebrovascular structure, blood-flow patterns, perfusion, or neurovascular coupling across time. This capability is relevant for studying disease progression and for monitoring vascular function as neurological conditions or experimental observations evolve.