Resting State Networks
Resting State Networks - Related Videos
10:43
Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
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Cited by 12 •
2014
This protocol describes the complementary neuroimaging techniques of resting state structural connectivity, task-induced deactivation, and structural connectivity analyses to examine the default network in post-traumatic stress disorder. The use of synergistic methods could potentially lead to improved diagnostics and assessments of severity, outcome, and other relevant clinical factors.
01:21
The Resting Membrane Potential
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2019
Overview The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane. The Inside of a Neuron Is More Negative The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular...
01:15
Resting Potential Decay
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2024
The resting membrane potential of a neuron (-70mV) is sustained due to the selective ion permeability of the membrane. At the resting potential, the membrane is slightly permeable to ions like sodium (Na+) and chloride (Cl−) and highly permeable to potassium ions (K+). Differences in the ions' concentration inside the cell compared to the outside are maintained by membrane transport proteins like channels and pumps. At rest, the K+ is the main ion that moves across the membrane through...
01:24
Resting Membrane Potential
0 Views •
2023
The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane. The Inside of a Neuron is More Negative The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...
01:11
Pressure Variation in a Fluid at Rest
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2025
In a fluid at rest, the pressure at any point beneath the fluid surface depends solely on the depth, not on the container's shape or size. This principle, known as hydrostatic pressure, arises because, in stationary fluids, there is no acceleration, meaning the forces within the fluid balance out. Only vertical forces, caused by the weight of the fluid above, contribute to pressure changes with depth. When measuring pressure at two different levels within the fluid, the difference in pressure...
FAQs
Researchers examine slow fluctuations in neural or blood-oxygen-level-dependent signals recorded while participants are not completing a specific task. Brain regions whose fluctuations show coordinated timing are treated as functionally connected. This approach reveals organized relationships among regions without requiring participants to perform an experimental behavior, helping characterize the brain’s intrinsic organization.
Functional connectivity describes the degree to which activity patterns in separate brain regions vary together. It does not simply identify which regions are anatomically adjacent; instead, it maps coordinated signal behavior across the brain. Comparing these relationships helps researchers distinguish network organization and examine how coordination changes across development, individuals, consciousness, or clinical conditions.
Different networks are associated with different broad aspects of brain function. The default mode network relates to self-directed thought, sensory networks support processing of perceptual information, attention networks help organize attentional activity, and executive control networks contribute to cognitive control. Examining these systems together provides a broader view than studying any single brain region alone.
A typical investigation records blood-oxygen-level-dependent signals while a participant rests rather than performs a designated task. Researchers then assess low-frequency signal fluctuations and evaluate functional connectivity among brain regions. The resulting patterns can be used to identify organized networks and compare their arrangement or coordination across participants, developmental stages, states of consciousness, or conditions.
Their organization provides a way to examine how intrinsic brain coordination varies across people and changes over development. Because the method does not depend on performance of a particular task, researchers can focus on differences in network arrangement and connectivity themselves. These measurements support investigations of how brain organization relates to developmental processes and variation between individuals.
Researchers can compare network organization or functional connectivity between typical and affected populations to identify changes associated with neurological or psychiatric conditions. The approach may also clarify whether alterations involve systems linked to self-directed thought, perception, attention, or cognitive control. In neuroscience, these comparisons connect measurable brain activity patterns with broader changes in brain function.