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Mappatura dei circuiti neuronali inibitori da fotostimolazione scansione laser

Article DOI: 10.3791/3109-v • 09:50 min • October 6th, 2011
October 6th, 2011 •
1, 1, 1, 1,2
1Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, 2Department of Biomedical Engineering, School of Engineering, University of California, Irvine

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Questo documento introduce un approccio di combinare fotostimolazione scansione laser con registrazioni cellula intera in topi transgenici che esprimono GFP in popolazioni limitate neuroni inibitori. La tecnica permette per la mappatura estesa e analisi quantitativa dei locali circuiti sinaptici di specifici neuroni inibitori corticali.

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Neuroscienze Numero 56 uncaging glutammato tutta la registrazione delle cellule GFP transgenici interneuroni
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