Name: 2013年7月在朱庇特的这个月 (视频) | JoVE Journal
Uploaded: 2013-07-01T20:00:00.000+00:00
Duration: 3 min 2 s
Description: 了解斑马鱼肌肉生理学、植物生物制药、啮齿动物攻击行为、银屑病临床治疗和DNA纳米技术的创新实验方法。本期JoVE展示了推动基础与应用科学发展的多样化研究技术与模型系统。

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5 minutes

<h2 class="jove_title"><a href="https://www.jove.com/video/4367">居民入侵者范式：侵略、暴力和社会压力的标准化测试</a></h2>
Jaap M. Koolhaas1， Caroline M. Coppens1， Sietse F. de Boer1， Bauke Buwalda1， Peter Meerlo1， Paul J.A. Timmermans2
1 格罗宁根大学行为与神经科学中心行为生理学系，2奈梅亨拉德堡德大学
该视频展示了大鼠的居民-入侵者范式。该测试是一种在半自然环境中测量攻击性、防御性行为和暴力的标准化方法。还解释了该范式在社会压力实验中的使用。
<h2 class="jove_title"><a href="https://www.jove.com/video/50268">用 DNA 折纸设计生物响应机器人</a></h2>
Eldad Ben-Ishay， Almogit Abu-Horowitz， Ido Bachelet
<a href='/institutions/AS-asia/IL-israel/574-bar-ilan-university'>巴伊兰大学生命科学学院和纳米技术与先进材料研究所</a>
DNA 折纸是一种通过对 DNA 分子的自组装进行编程来制造精确纳米级物体的强大方法。在这里，我们描述了如何利用 DNA 折纸来设计一个机器人，该机器人能够感知生物线索并通过形状变化做出反应，随后传达到所需的效果。
<h2 class="jove_title"><a href="https://www.jove.com/video/50509">治疗中度至重度银屑病的 Goeckerman 方案</a></h2>
 Rishu Gupta1,2， Maya Debbaneh2,3， Daniel Butler2,4， Monica Huynh2,5， Ethan Levin2， Argentina Leon2， John Koo2， Wilson Liao2
1<a href='/institutions/NA-north-america/US-united-states/CA-california/16311-university-of-southern-california'>南加州大学凯克医学院</a>，2<a href='/institutions/NA-north-america/US-united-states/CA-california/23335-university-of-california-san-francisco'>加利福尼亚大学旧金山分校皮肤科银屑病和皮肤治疗中心，</a>3加州大学尔湾分校医学院、4亚利桑那大学医学院、5芝加哥骨科医学院
银屑病是一种慢性免疫介导的炎症性皮肤病。Goeckerman 方案用于治疗银屑病，包括暴露于紫外线 B （UVB） 光和涂抹粗煤焦油 （CCT）。以下方案用于 Goeckerman 疗法治疗中度至重度银屑病。
<h2 class="jove_title"><a href="https://www.jove.com/video/50521">植物高效农林渗透，用于重组蛋白的高水平瞬时表达</a></h2>
Kahlin Leuzinger*， Matthew Dent*， Jonathan Hurtado， Jake Stahnke， Huafang Lai， Xiaohong 周， Qiang Chen
<a href='/institutions/NA-north-america/US-united-states/AZ-arizona/19026-arizona-state-university'>亚利桑那州立大学生物设计研究所技术与创新学院传染病与疫苗学中心</a>
Plants 提供了一种新型系统，用于商业规模的药物蛋白生产，该系统比目前的表达范式更具可扩展性、成本效益和安全性。在这项研究中，我们报道了一种简单方便但可扩展的方法，将含有根癌农杆菌的靶基因引入植物中以进行蛋白质瞬时表达。
<h2 class="jove_title"><a href="https://www.jove.com/video/50539">收缩过程中的力测量以评估斑马鱼幼虫的肌肉功能</a></h2>
Darcée D. Sloboda1， Dennis R. Claflin1,2， James J. Dowling3， Susan V. Brooks1,4
1<a href='/institutions/NA-north-america/US-united-states/MI-michigan/1888-university-of-michigan-ann-arbor'>密歇根大学生物医学工程系</a>，2<a href='/institutions/NA-north-america/US-united-states/MI-michigan/1888-university-of-michigan-ann-arbor'>密歇根大学整形外科外科</a>系，3<a href='/institutions/NA-north-america/US-united-states/MI-michigan/1888-university-of-michigan-ann-arbor'>密歇根大学儿科和神经病学系</a>，4<a href='/institutions/NA-north-america/US-united-states/MI-michigan/1888-university-of-michigan-ann-arbor'>密歇根大学分子与综合生理学系</a>
力测量可用于显示由于发育、损伤、疾病、治疗或化学毒性引起的肌肉功能变化。在本视频中，我们演示了一种在斑马鱼幼鱼躯干肌肉最大收缩过程中测量力的方法。

No conflicts of interest declared.

july 2013: this month in jove

July 2013: This Month in JoVE

Here's a look at what's coming up in the <a href="http://www.jove.com/archive/77" target="_blank">July 2013 issue</a> of <a href="http://www.jove.com/" target="_blank">JoVE: The Journal of Visualized Experiments.</a>
This month, we take a dip in the zebrafish tank and use this classical laboratory model to study muscle function. <a href="http://www.jove.com/video/50539" target="_blank">Sloboda, et al.</a> measure force generation during trunk muscle contraction in zebrafish larvae. This is done by attaching the larvae to a force transducer and a length controller; the authors then apply an electrical field to stimulate the muscle fibers, and determine the force-generating capacity of the larval muscles. This gives a useful measure of muscle function and overall health.
<a href="http://www.jove.com/video/50521" target="_blank">Leuzinger, et al.</a> combine farming with pharma in demonstrating a transgenic plant-based system for expressing biopharmaceuticals on an agricultural scale. The authors agroinfiltrate plant leaves with viral vectors to induce high-level transient expression of recombinant proteins, which can lead to large-scale pharmaceutical production to meet increasing worldwide demands.
Moving on to <a href="http://www.jove.com/behavior?utm_source=tmij" target="_blank">JoVE Behavior</a>, we highlight an article on aggression, which is a natural response to intruders in virtually all animals. <a href="http://www.jove.com/video/4367" target="_blank">Koolhaas, et al.</a> demonstrate the resident-intruder paradigm in rats and illustrate various natural behaviors against intruders, including social exploration, lateral threat, chase, and attack.
In <a href="http://www.jove.com/ctm" target="_blank">JoVE Clinical and Translational Medicine</a>, we focus on psoriasis, a chronic inflammatory skin disease. <a href="http://www.jove.com/video/50509" target="_blank">Gupta, et al.</a> demonstrate the Goeckerman regimen, a psoriasis treatment that applies ultraviolet B (UVB) phototherapy Followed by crude coal tar (CCT). Developed in 1925 by the American dermatologist William H. Goeckerman, this treatment has an excellent safety profile compared to immune-suppressing drugs, and is extremely effective in treating psoriasis.
Finally, in <a href="http://www.jove.com/bioeng" target="_blank">JoVE Bioengineering</a>, we highlight the incredible versatility of nucleic acids. Besides storing information that directs countless biological processes, nucleic acids can be programmed to self-assemble into two-dimensional and three-dimensional structures. <a href="http://www.jove.com/video/50268" target="_blank">Ben-Ishay, et al.</a> use caDNAno software to design DNA origami nanorobots, which can sense biological cues and exert specific effects. These nanorobots harness the remarkable features of DNA and may advance the field of nanotechnology with a broad range of potential therapeutic and industrial applications. 
You&#x2019;ve just had a sneak peek of a few highlights from the <a href="http://www.jove.com/archive/77" target="_blank">July 2013 issue</a>. Visit the website to see the full-length articles and many more in <a href="http://www.jove.com/" target="_blank">JoVE: The Journal of Visualized Experiments.</a>

Here are some highlights from the July 2013 Issue of Journal of Visualized Experiments (JoVE).

Here's a look at what's coming up in the July 2013 issue of JoVE: The Journal of Visualized Experiments.
This month, we take a dip in the zebrafish tank ...

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2013年7月在朱庇特的这个月

了解斑马鱼肌肉生理学、植物生物制药、啮齿动物攻击行为、银屑病临床治疗和DNA纳米技术的创新实验方法。本期JoVE展示了推动基础与应用科学发展的多样化研究技术与模型系统。

2013年7月在朱庇特的这个月 (视频) | JoVE Journal

Wendy Chao

Aaron Kolski-Andreaco

July 2013: This Month in JoVE

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