Polycarbonate Silicon Devices

Polycarbonate silicon devices are hybrid bioengineering platforms that combine a polycarbonate polymer component with silicon to support biological analysis, sensing, or microscale fluid handling. Their function arises from complementary material properties: silicon can provide patterned microstructures and electronic or photonic elements, while polycarbonate can form lightweight, moldable, insulating, and optically accessible chambers or channels; fabrication may join the materials through aligned assembly and bonding. These devices enable compact lab-on-a-chip systems for cell studies, biosensing, diagnostics, and controlled delivery, linking semiconductor manufacturing with polymer processing to create integrated tools that reduce sample volumes and support high-throughput experimentation.

Polycarbonate Silicon Devices - Related Videos

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JoVE Journal - Bioengineering

Construction Methods for Hybrid Polycarbonate-Silicon Microfluidic Devices

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2026

This protocol describes three straightforward sealing methods for fabricating a hybrid microfluidic device that integrates polycarbonate and silicon components. By implementing solvent bonding, thermal compression, and mechanical compression strategies, we enable reliable, low-temperature sealing techniques that avoid specialized equipment for hybrid microfluidic devices.

Research

JoVE Journal - Bioengineering
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Polydimethylsiloxane-polycarbonate Microfluidic Devices for Cell Migration Studies Under Perpendicular Chemical and Oxygen Gradients

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Cited by 13 •

2017

The control of chemical and oxygen gradients is essential for cell cultures. This paper reports a polydimethylsiloxane-polycarbonate (PDMS-PC) microfluidic device capable of reliably generating combinations of chemical and oxygen gradients for cell migration studies, which can be practically utilized in biological labs without sophisticated instrumentation.

A 3D-Printed Silicone-Coated Device to Model Catheter-Associated Urinary Tract Infection

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2025

Source:Ocean E. Clarke1, Romy A. Dop1, Tom Hasell1, Joanne L. Fothergill1, Daniel R. Neill21University of Liverpool, 2 University of DundeeThis video demonstrates the use of a 3D-printed, silicone-coated device that mimics the inner surface of urinary catheters to simulate catheter-associated urinary tract infection.

Epitaxial Nanostructured α-Quartz Films on Silicon: From the Material to New Devices

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Cited by 2 •

2020

This work presents a detailed protocol for the microfabrication of nanostructured α-quartz cantilever on a Silicon-On-Insulator(SOI) technology substrate starting from the epitaxial growth of quartz film with the dip coating method and then nanostructuration of the thin film via nanoimprint lithography.

Thermal Measurement Techniques in Analytical Microfluidic Devices

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Cited by 6 •

2015

Here, we present three protocols for thermal measurements in microfluidic devices.

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