Fibrous Cartilage

Fibrous cartilage is a tough, flexible connective tissue that combines the tensile strength of dense collagen fibers with the resilience of cartilage, helping tissues withstand compression and shear. Its matrix contains abundant, parallel bundles of type I collagen and rows of chondrocytes, while limited vascularization contributes to slow repair after injury. Found in intervertebral discs, the pubic symphysis, and menisci, fibrous cartilage stabilizes joints, distributes mechanical loads, and absorbs shock during movement. Understanding its structure and biomechanics supports research into spinal disorders, sports injuries, tissue degeneration, and strategies for cartilage repair and regenerative medicine.

Fibrous Cartilage - Related Videos

Education

JoVE Core - Molecular Biology

Globular and Fibrous Proteins

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2020

Many proteins can be classified into two distinct subtypes - globular or fibrous. These two types differ in their shapes and solubilities. Globular proteins are also known as spheroproteins and typically are approximately round in shape. They contain a mix of amino acid types and contain differing sequences in their primary structures. Globular proteins have many different functions, such as enzymes, cellular messengers, and molecular transporters. These roles often require the proteins to be...

Fibrous Proteins

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2023

Fibrous proteins are either long and narrow proteins or assemble to form long and thin structures. They contain repetitive units and usually consist of either alpha helices or beta sheets and, in rare cases, a mix of both. The amino acids in the primary structure often consist of repeating amino acid sequences. The role of fibrous proteins is primarily structural. Many are located in the extracellular matrix and are present in connective tissues to impart strength and joint mobility. They are...

Structural Joints: Fibrous Joints

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2025

Fibrous joints are a type of joint where the bones are connected by fibrous connective tissue. These joints provide stability and minimal to no movement between the articulating bones. There are three types of fibrous joints. Suture All the bones of the skull, except for the mandible, are joined to each other by a fibrous joint called a suture. The fibrous connective tissue found at a suture strongly unites the adjacent skull bones and thus helps to protect the brain and form the face. In...

Research

JoVE Journal - Bioengineering
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In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen

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Cited by 16 •

2012

Simple and reproducible procedures are described for making three structurally distinct collagen assemblies from a common commercially available Type I collagen monomer. Native type, fibrous long spacing or segmental long spacing collagen can be constructed by varying the conditions to which the 300 nm long and 1.4 nm diameter monomer building block is exposed.

Electrospinning Growth Factor Releasing Microspheres into Fibrous Scaffolds

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Cited by 10 •

2014

This protocol combines electrospinning and microspheres to develop tissue engineered scaffolds to direct neurons. Nerve growth factor was encapsulated within PLGA microspheres and electrospun into Hyaluronic Acid (HA) fibrous scaffolds. The protein bioactivity was tested by seeding the scaffolds with primary chick Dorsal Root Ganglia and culturing for 4-6 days.

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