Rest And Digest System

The rest and digest system is the part of the autonomic nervous system that supports calm physiological activity, energy conservation, and digestion after stress or exertion. Primarily through parasympathetic nerves, including the vagus nerve, it releases acetylcholine to slow heart rate, constrict pupils, stimulate salivary and digestive secretions, and promote intestinal movement. This system helps maintain homeostasis by directing resources toward nutrient processing, absorption, and tissue maintenance rather than rapid action. Studying its regulation is important in biology and medicine because altered parasympathetic activity can affect cardiovascular function, gastrointestinal health, stress recovery, and the balance between sympathetic and parasympathetic responses.

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JoVE Core - Biology

The Resting Membrane Potential

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2019

Overview The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane. The Inside of a Neuron Is More Negative The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular...

Resting Potential Decay

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2024

The resting membrane potential of a neuron (-70mV) is sustained due to the selective ion permeability of the membrane. At the resting potential, the membrane is slightly permeable to ions like sodium (Na+) and chloride (Cl−) and highly permeable to potassium ions (K+). Differences in the ions' concentration inside the cell compared to the outside are maintained by membrane transport proteins like channels and pumps. At rest, the K+ is the main ion that moves across the membrane through...

Resting Membrane Potential

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2023

The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane. The Inside of a Neuron is More Negative The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...

Restriction Enzyme Digests

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2023

Restriction enzymes or endonucleases recognize and cut DNA at a specific sequence. These enzymes occur naturally in bacteria as a defense against bacteriophages - viruses that infect bacteria. Bacterial restriction enzymes cut the invading bacteriophage DNA while leaving the bacterial genomic DNA unharmed due to addition of methyl groups. This video explains the basic principles of restriction enzymes including: how restriction enzymes are named and the types of recognition sites and...

Pressure Variation in a Fluid at Rest

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2025

In a fluid at rest, the pressure at any point beneath the fluid surface depends solely on the depth, not on the container's shape or size. This principle, known as hydrostatic pressure, arises because, in stationary fluids, there is no acceleration, meaning the forces within the fluid balance out. Only vertical forces, caused by the weight of the fluid above, contribute to pressure changes with depth. When measuring pressure at two different levels within the fluid, the difference in pressure...

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