Glucose Biosensor

A glucose biosensor is an analytical device that detects and measures glucose concentration by converting a biochemical reaction into a measurable signal. In many designs, the enzyme glucose oxidase selectively reacts with glucose, producing electrons or hydrogen peroxide; an electrochemical transducer then converts this reaction into an electrical current proportional to glucose levels. Engineering principles guide the choice of enzymes, electrode materials, membranes, and signal-processing methods to improve sensitivity, selectivity, stability, and response time. These devices support blood-glucose monitoring, wearable health technologies, biomedical research, and process control, while continued advances aim to enable smaller, more reliable, and minimally invasive sensing systems.

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In Vitro Glucose Depletion Assay: A Fluorescence-Based Method to Quantify Cellular Glucose Uptake via Extracellular Glucose Depletion Measurement

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2025

This video demonstrates an in vitro assay to indirectly measure intracellular glucose uptake. The assay uses a fluorescently-labeled glucose analog to establish a correlation between extracellular glucose depletion and intracellular glucose uptake.

Oral Glucose Tolerance Test (OGTT): Measuring Glucose Metabolism in Mice

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2023

This video introduces how to perform an oral glucose tolerance test on a laboratory mouse.

NiO Nanoflowers for Non-Enzymatic Amperometric Detection of Glucose

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2025

The primary objective of this article is to help researchers and scientists understand the process of glucose sensing using electrochemistry and to optimize parameters to maximize the glucose sensing response. The process of fabricating a glucose sensor is described in detail with guidelines for obtaining its best chronoamperometric response.

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

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Cited by 17 •

2013

Lytic phage biosensors and antibody beads are able to discriminate between methicillin resistant (MRSA) and sensitive staphylococcus bacteria. The phages were immobilized by a Langmuir-Blodgett method onto a surface of a quartz crystal microbalance sensor and worked as broad range staphylococcus probes. Antibody beads recognize MRSA.

In Vivo Biosensor Tracks Non-apoptotic Caspase Activity in Drosophila

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Cited by 5 •

2016

To detect healthy cells in whole animals that contain low levels of caspase activity, the highly sensitive biosensor designated CaspaseTracker was generated for Drosophila. Caspase-dependent biosensor activity is detected in long-lived healthy cells throughout the internal organs of adult animals reared under optimized conditions in the absence of death stimuli.

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