Nucleation Rate
Nucleation Rate - Related Videos
09:53
Automated Microfluidic Blood Lysis Protocol for Enrichment of Circulating Nucleated Cells
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Cited by 4 •
2009
An automated microfluidic device was developed for circulating nucleated cell enrichment from peripheral blood via erythrocyte lysis that ensures isolation of high quality sample without cell loss.
09:41
Visualization of Cell Cycle Variations and Determination of Nucleation in Postnatal Cardiomyocytes
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Cited by 5 •
2017
To distinguish cell division from cell cycle variations in cardiomyocytes, we present protocols using two transgenic mouse lines: Myh6-H2B-mCh transgenic mice, for the unequivocal identification of cardiomyocyte nuclei, and CAG-eGFP-anillin mice, for distinguishing cell division from cell cycle variations.
09:36
The Use of High-resolution Infrared Thermography (HRIT) for the Study of Ice Nucleation and Ice Propagation in Plants
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Cited by 27 •
2015
Here we present a protocol that allows one to visualize sites of ice formation and avenues of ice propagation in plants utilizing high resolution infrared thermography (HRIT).
10:10
Synthesis of Compound Giant Unilamellar Vesicles: A Biomimetic Model of Nucleate Cells
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2025
This article presents a method for preparing compound Giant Unilamellar Vesicles (cGUVs) with a vesicle-in-vesicle structure, with customized electrical conductivity in inner, annular, and outer regions. Electroformation synthesizes simple GUVs, which are transformed into stomatocytes and cGUVs via osmotic shock, providing a valuable model for studying the biophysics of nucleated cells.
02:53
Reaction Rate
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2020
The rate of reaction is the change in the amount of a reactant or product per unit time. Reaction rates are therefore determined by measuring the time dependence of some property that can be related to reactant or product amounts. Rates of reactions that consume or produce gaseous substances, for example, are conveniently determined by measuring changes in volume or pressure. The mathematical representation of the change in the concentration of reactants and products, over time, is the rate...
FAQs
A new phase cannot form stably until the energetic cost of creating its interface is overcome. Supersaturation or undercooling supplies the driving condition needed to cross this barrier, while interfacial energy determines how difficult that transition is. Consequently, small changes in temperature, composition, or surface conditions can substantially alter the frequency of successful nucleus formation.
Homogeneous nucleation occurs within the material without a preferred external surface, whereas heterogeneous nucleation is assisted by an existing surface. Because surfaces influence the interfacial conditions for forming a new phase, the two pathways can produce different nucleation rates under otherwise similar conditions. This distinction is important when interpreting structures formed during solidification, crystallization, or thin-film growth.
Temperature, composition, supersaturation, undercooling, interfacial energy, and the presence of surfaces all affect nucleation behavior. Temperature and composition determine whether the system reaches conditions favorable for forming a stable phase, while interfacial energy and surfaces influence the energetic difficulty of creating it. Their combined effects help determine the resulting crystal size, grain structure, and porosity.
Engineers use nucleation-rate information to connect processing conditions with the structure that develops in a material. Quantifying the rate supports design decisions for solidification, crystallization, precipitation, and thin-film growth. The resulting predictions can guide materials optimization by relating phase-transformation behavior to crystal size, grain structure, and porosity in manufactured components.
Adjusting nucleation rate changes how many stable nuclei form during a phase transformation and therefore influences the structure produced as the material develops. In engineering processes, this control can be used to tailor crystal size, grain structure, and porosity. Such structural changes are relevant because they affect the organization and quality of the final manufactured component.
Nucleation rate is relevant wherever a new phase forms and its structure affects processing or performance. Important examples include solidification, crystallization, precipitation, and thin-film growth. Studying the rate in these settings helps engineers optimize materials and process conditions, quantify phase-transformation behavior, and support predictions about the structure and performance of manufactured components.