Tilting Drum Mixers
Tilting Drum Mixers - Related Videos
12:42
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Cited by 9 •
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In this work we explain the fabrication and use of a microfluidic mixer capable of mixing two solutions in ~8 μs. We also demonstrate the use of these mixers with spectroscopic detection using UV fluorescence and fluorescence resonance energy transfer (FRET).
02:32
Generation of Tilted Amygdala Slices from a Mouse Brain
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The video demonstrates the generation of tilted amygdala slices from a mouse brain. The brain is positioned at an angle on the vibratome specimen stage to obtain slices containing the amygdala and axons from the medial prefrontal cortex that form synaptic connections with the amygdala. The brain slices are maintained at the physiological temperature to preserve the tissue for further experiments.
14:09
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12:10
Single Particle Electron Microscopy Reconstruction of the Exosome Complex Using the Random Conical Tilt Method
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Cited by 35 •
2011
This article describes a standard method to get a three-dimensional (3D) reconstruction of biological macromolecules using negative staining electron microscopy (EM). In this protocol, we explain how to get the 3D structure of the Saccharomyces cerevisiae exosome complex at medium resolution using the random conical tilt reconstruction method (RCT).
08:10
Synthesizing Lipid Nanoparticles by Turbulent Flow in Confined Impinging Jet Mixers
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Cited by 20 •
2024
A detailed protocol for synthesizing lipid nanoparticles (LNPs) using confined impinging jet (CIJ) mixer technologies, including a two-jet CIJ and a four-jet multi-inlet vortex mixer (µMIVM), is demonstrated. The CIJ mixers generate reproducible, turbulent micro-mixing environments, resulting in the production of monodisperse LNPs.
FAQs
As the drum rotates around its inclined axis, the load is carried upward and then falls through the drum under gravity. This repeated lifting and cascading redistributes cement, aggregates, water, mortar components, or other materials throughout the batch. Continued cycling reduces local concentration differences and supports a more uniform mixture before discharge.
Drum speed, tilt angle, mixing time, and material proportions jointly affect the result. Speed controls how frequently the load is lifted and released, while inclination influences both tumbling behavior and material movement. Mixing time determines how long redistribution continues, and component proportions affect how readily the materials combine into a uniform batch.
The drum angle serves different handling purposes during the batch cycle. An inclined axis helps materials participate in gravity-driven movement during rotation, while changing the angle supports charging at the beginning and controlled discharge afterward. This makes inclination an operational control for both internal mixing behavior and the movement of materials into or out of the drum.
Their operation is organized around individual batches rather than an uninterrupted material stream. Components are loaded, mixed for a selected period, and discharged before another batch is handled. This batch arrangement supports flexible batch sizes and suits construction work where concrete or mortar may need to be prepared as material handling and placement proceed.
A typical cycle uses the drum angle to support charging, rotates the drum while the materials tumble, and changes the inclination when the batch is ready for discharge. Operators select mixing time and monitor the relationship among drum speed, angle, and material proportions. The sequence provides a controlled path from loading to a more uniform batch and final emptying.
Construction applications commonly combine cement, aggregates, and water to produce concrete, or use appropriate material combinations to produce mortar. The same handling principle can also blend other materials in industrial settings, although the overview specifically identifies construction mixtures and broader industrial material handling as important uses. Material proportions remain central to the resulting batch.
They are useful when a site needs practical production of concrete or mortar in separate batches rather than relying on one fixed output volume. Their flexible batch sizes and adjustable drum position support material handling during loading and controlled emptying. These characteristics make them relevant to construction environments where mixing and handling must occur close to the work.
The primary outcome is whether the cement, aggregates, water, or other selected components have become sufficiently uniform throughout the batch. Evaluation should consider the chosen mixing time, drum speed, tilt angle, and material proportions because each can influence the result. In engineering practice, this assessment connects machine settings with the consistency required for concrete, mortar, or another handled mixture.