Duodenal Tumor Excision
Duodenal Tumor Excision - Related Videos
06:43
Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib
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2026
This video case report demonstrates the unique management of a duodenal gastrointestinal stromal tumor with a rare, understudied, exon 8 KIT mutation. Neoadjuvant therapy resulted in a 30% reduction in tumor size, making the patient a candidate for a robotic-assisted duodenal sleeve resection instead of the more morbid pancreaticoduodenectomy.
01:54
Base Excision Repair
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2020
One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template. The first step of...
03:37
Application of Robot-assisted Pancreaticobiliary Junction Resection in Benign Duodenal Tumors
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2024
The current protocol delineates the use of robot-assisted pancreaticobiliary junction resection for the surgical management of benign duodenal tumors. This approach provides an effective solution for treating these tumors while minimizing duodenal loss and reducing associated complications.
11:32
Analytical Determination of Mitochondrial Function of Excised Solid Tumor Homogenates
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Cited by 4 •
2021
We developed a practical protocol and analytical approach to evaluate mitochondrial oxidative phosphorylation and electron transfer capacity in fresh tumor homogenates. This protocol can be easily adapted to survey various mitochondrial functions that contribute to cancer initiation, progression, and treatment response.
08:56
Terahertz Imaging and Characterization Protocol for Freshly Excised Breast Cancer Tumors
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Cited by 18 •
2020
Freshly excised human breast cancer tumors are characterized with terahertz spectroscopy and imaging following fresh tissue handling protocols. Tissue positioning is taken into consideration to enable effective characterization while providing analysis in a timely manner for future intraoperative applications.
FAQs
These factors determine whether the lesion can be removed locally or requires a more extensive regional resection. A tumor’s position affects surgical access, while its size and relationship to nearby structures influence the amount of tissue that must be removed. Planning therefore balances disease control against preservation of intestinal continuity and digestive function.
Removing the lesion with an appropriate margin helps address the tumor while limiting unnecessary loss of healthy duodenal tissue. The required extent depends on the tumor’s characteristics and local involvement rather than a single standard measurement. This balance can support disease control while reducing the impact of resection on the intestinal wall and subsequent reconstruction.
Regional resection may be considered when a tumor is extensive or cannot be separated adequately from surrounding tissue. A limited approach is more compatible with preserving local anatomy when feasible, whereas broader removal addresses involvement beyond the immediate lesion. The choice reflects the tumor’s size, location, and relationship to adjacent structures identified during planning.
The excised tissue undergoes histopathological examination, which provides the definitive diagnosis described for the procedure. This analysis allows the removed lesion to be characterized after surgery rather than relying only on its appearance or location. The result supplies essential information for interpreting the operation and determining the significance of the tissue that was removed.
The operation begins by exposing and locating the lesion. Surgeons then separate it from surrounding tissue, remove it with an appropriate margin, and control bleeding. After excision, they close or reconstruct the intestinal wall. If the tumor extends more broadly, the procedure may progress to regional resection rather than ending with local removal.
Bleeding control is performed after or during tumor separation and removal to support a safe operative field. The resulting intestinal-wall defect is then closed or reconstructed according to the extent of tissue removed. These steps are important because the operation must address the lesion while maintaining, when possible, the continuity needed for passage of intestinal contents.
By removing the lesion, surgery can relieve or prevent problems caused by its presence in the duodenum, including obstruction, bleeding, and impaired passage of intestinal contents. The procedure also yields tissue for definitive diagnosis. Its clinical value therefore includes both managing local complications and clarifying the nature of the tumor through histopathological assessment.