Human Pancreas Dissection

Human pancreas dissection is the systematic exposure and examination of the pancreas to understand its structure, relationships, and clinical significance. Through careful separation of surrounding tissues, the procedure reveals the gland’s head, neck, body, and tail, along with its connections to the duodenum, spleen, biliary tract, and major blood vessels; examination also distinguishes its exocrine and endocrine organization. In medicine, this anatomical method supports practical education, interpretation of imaging and pathology, and understanding of conditions such as pancreatitis, tumors, and duct obstruction. It also provides a foundation for safer abdominal surgery and improved clinical reasoning.

Human Pancreas Dissection - Related Videos

Research

JoVE Journal - Medicine

Collection Protocol for Human Pancreas

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Cited by 32 •

2012

This video demonstrates a dissection procedure for processing human pancreas into multiple storage formats. Anatomical orientation is maintained throughout the pancreatic regions to allow definition of regional islet composition and density.

Dissection of the Mouse Pancreas for Histological Analysis and Metabolic Profiling

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Cited by 14 •

2017

This video article provides a detailed demonstration of the procedures required to successfully remove the pancreas from a mouse by dissection for histological analysis and metabolic profiling.

A System for ex vivo Culturing of Embryonic Pancreas

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Cited by 23 •

2012

Here, we describe a method for isolation, culture and manipulation of mouse embryonic pancreas. This represents an excellent ex vivo system for studying various aspects of pancreatic development, including morphogenesis, differentiation and growth. Pancreatic bud explants can be cultured for several days and used in a range of different applications, including whole-mount immunofluorescence and live imaging.

In Vitro Pancreas Organogenesis from Dispersed Mouse Embryonic Progenitors

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Cited by 26 •

2014

The three-dimensional culture method described in this protocol recapitulates pancreas development from dispersed embryonic mouse pancreas progenitors, including their substantial expansion, differentiation and morphogenesis into a branched organ. This method is amenable to imaging, functional interference and manipulation of the niche.

Education

JoVE Core - Anatomy and Physiology

Pancreas

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2024

The pancreas, an essential organ in the human body, is a pinkish-gray elongated structure located posterior to the stomach. It extends laterally from the duodenum towards the spleen and is firmly bound to the posterior wall of the abdominal cavity. The organ's surface has a lumpy, lobular texture that gives it a unique appearance. The broad head of the pancreas lies within the loop formed by the duodenum, while its slender body reaches towards the spleen. The tail of the pancreas is short and...

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