Permanent Implantation Surgery

Permanent implantation surgery is a medical procedure that places a device, prosthesis, or other biocompatible material inside the body for long-term therapeutic or functional support. Surgeons create a controlled operative pathway, position the implant at the intended anatomical site, and secure it while maintaining sterile conditions; healing may stabilize the implant through tissue integration or a fibrous capsule. Applications include structural replacement, restoration of bodily function, and delivery or support systems that require durable placement. Successful implantation depends on appropriate device selection, precise surgical technique, biocompatibility, and monitoring for complications such as infection, displacement, or tissue reactions.

Permanent Implantation Surgery - Related Videos

Research

JoVE Journal - Medicine

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

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2026

The Foldable Capsular Vitreous Body (FCVB) is an intraocular implant that encapsulates silicone oil within a flexible capsule to reduce silicone oil-related complications. This protocol describes the surgical implantation of the FCVB via scleral incision for the treatment of complex retinal detachment and ocular trauma.

The Application Of Permanent Middle Cerebral Artery Ligation in the Mouse

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Cited by 29 •

2011

Middle cerebral artery (MCA) ligation is a technique to study focal cerebral ischemia in animal models. In this method, the middle cerebral artery is exposed by craniotomy and ligated by cauterization. This method gives highly reproducible infarct volumes and increased post-operative survival rates compared to other methods available.

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection

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Cited by 14 •

2013

We describe a highly reproducible method for the permanent occlusion of a rodent major cerebral blood vessel. This technique can be accomplished with very little peripheral damage, minimal blood loss, a high rate of long-term survival, and consistent infarct volume commensurate with the human clinical population.

Research

JoVE Journal - Medicine
Free Sample

Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery

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Cited by 103 •

2014

Various murine models of middle cerebral artery occlusion (MCAO) are widely used in experimental brain research. Here, we demonstrate the model of transcranial permanent distal MCAO which produces consistent cortical infarction of a size corresponding to damage imposed by the majority of human ischemic strokes.

Implantation of Left Ventricular Assist Device (LVAD) in Juvenile Landrace Swine: A LVAD Implantation Model of Pediatric Heart Failure

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Cited by 1 •

2026

This article presents a protocol to implant the left ventricular assist device (LVAD) into a piglet. This model represents a potent way to study the LVAD implantation in children and reveal the mechanism of ventricular reverse remodeling in LVAD treatment.

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