Bidirectional Lstm

Bidirectional long short-term memory (BiLSTM) is a recurrent neural network architecture for modeling sequential data, using information from both preceding and following time points to represent each element in a sequence. It combines two LSTM pathways, one processing data forward and the other backward; input, forget, and output gates regulate information stored in each memory cell, and the pathways’ hidden states are combined. In neuroscience, BiLSTMs can analyze EEG and other neural time series for brain-state classification, event detection, and neural decoding. Their access to future samples improves contextual interpretation in offline analyses, but limits use when real-time predictions cannot wait for later data.

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Research

JoVE Journal - Bioengineering
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Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts

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2025

This protocol outlines advanced material fabrication and ex vivo rat heart methods for optical and electrical bidirectional biointerfacing, enabling precise cardiac stimulation, recording, and infarction modeling for bioelectronics research.

Research

JoVE EoE - Neurophysiology

Implanting a Wireless Bidirectional Microelectrode System in a Rat Brain

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2025

The video demonstrates a procedure for implanting a wireless bidirectional multichannel electrode unit into a rat brain to record and stimulate multichannel neural networks.

Bidirectional Retroviral Integration Site PCR Methodology and Quantitative Data Analysis Workflow

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Cited by 5 •

2017

This manuscript describes the experimental procedure and software analysis for a bidirectional integration site assay that can simultaneously analyze upstream and downstream vector-host junction DNA. Bidirectional PCR products can be used for any downstream sequencing platform. The resulting data are useful for a high-throughput, quantitative comparison of integrated DNA targets.

Research

JoVE Journal - Behavior
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A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats

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Cited by 13 •

2017

A wireless, bidirectional system for multi-channel neural recordings and stimulation in freely behaving rats is introduced. The system is light and compact, thus having minimal impact on the animal´s behavioral repertoire. Moreover, this bidirectional system provides a sophisticated tool to assess causal relationships between brain activation patterns and behavior.

In vivo Visualization of Synaptic Vesicles Within Drosophila Larval Segmental Axons

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Cited by 16 •

2010

This protocol discusses the live dissection of Drosophila larvae for the purpose of imaging the movement of GFP tagged axonal vesicles on microtubule tracks.

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