Journal
/
Neurowissenschaften
/
The Tail Suspension Test
JoVE Journal
Neurowissenschaften
Author Produced
Zum Anzeigen dieser Inhalte ist ein JoVE-Abonnement erforderlich.  Melden Sie sich an oder starten Sie Ihre kostenlose Testversion.
JoVE Journal Neurowissenschaften
The Tail Suspension Test

The Tail Suspension Test

77,846 Views

•

10:17 min

•

January 28, 2012

DOI:

10.3791/3769-v

DOI:
10.3791/3769-v

•

10:17 min
January 28, 2012

•

113 Views
, , , , ,
1Department of Psychiatry,University of Maryland School of Medicine, 2Tulane University School of Medicine, 3The Program in Neuroscience,University of Maryland , 4Department of Pharmacology and Experimental Therapeutics,University of Maryland School of Medicine

Summary

Automatically generated

The tail-suspension test is validated as an experimental procedure to assess antidepressant efficacy of drug treatments in mice. Mice are suspended by their tails for six minutes and escape-related behaviors are assessed. We describe procedures used in conducting the tail suspension test.

Explore More Videos

Tail-suspension TestMouse Behavioral TestAntidepressant DrugsDepression-related BehaviorsHigh-throughput ScreeningDrug DiscoveryProspective Antidepressant CompoundsImplementation DetailsPotential ProblemsTail Climbing BehaviorC57BL/6 Mouse StrainPlastic CylinderManual Behavior Scoring

Read Article

Cite this Article

Can, A., Dao, D. T., Terrillion, C. E., Piantadosi, S. C., Bhat, S., Gould, T. D. The Tail Suspension Test. J. Vis. Exp. (59), e3769, doi:10.3791/3769 (2012).

Download .ris file

Copy

Share Video

.

Copy