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Construction and Characterization of a Novel Vocal Fold Bioreactor
JoVE Journal
Biotechnik
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JoVE Journal Biotechnik
Construction and Characterization of a Novel Vocal Fold Bioreactor
DOI:

11:11 min

August 01, 2014

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Kapitel

  • 00:05Titel
  • 01:15Scaffold Fabrication
  • 02:58Bioreactor Assembly
  • 05:34Bioreactor Characterization
  • 07:00Vibratory Cell Culture
  • 08:44Results: Vibration Induces Extra Cellular Matrix (ECM) Protein Expression in MSC Cultures
  • 10:44Conclusion

Summary

Automatische Übersetzung

A novel vocal fold bioreactor capable of delivering physiologically relevant, vibratory stimulation to cultured cells is constructed and characterized. This dynamic culture device, when combined with a fibrous poly(ε-caprolactone) scaffold, creates a vocal fold-mimetic environment that modulates the behaviors of mesenchymal stem cells.

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