Electrophysiological Motor Unit Number Estimation (MUNE) Measuring Compound Muscle Action Potential (CMAP) in Mouse Hindlimb Muscles

W. David Arnold; Kajri A. Sheth; Christopher G. Wier; John T. Kissel; Arthur H. Burghes; Stephen J. Kolb

doi:10.3791/52899

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Elektrophysiologische Motor Unit Number Estimation (MUNE) Mess Verbindung Muskelaktionspotenzial (CMAP) in Maus-Hinterlauf Muskeln

Electrophysiological Motor Unit Number Estimation (MUNE) Measuring Compound Muscle Action Potential (CMAP) in Mouse Hindlimb Muscles

JoVE Journal
Verhalten

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JoVE Journal Verhalten

Electrophysiological Motor Unit Number Estimation (MUNE) Measuring Compound Muscle Action Potential (CMAP) in Mouse Hindlimb Muscles

Elektrophysiologische Motor Unit Number Estimation (MUNE) Mess Verbindung Muskelaktionspotenzial (CMAP) in Maus-Hinterlauf Muskeln

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21,175 Views

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09:07 min

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September 25, 2015

DOI:

10.3791/52899-v

DOI:

10.3791/52899-v

•

09:07 min

September 25, 2015

•

21128 Views

W. David Arnold^1,2,3, Kajri A. Sheth¹, Christopher G. Wier⁴, John T. Kissel^1,3, Arthur H. Burghes^1,3,4, Stephen J. Kolb^1,3,4

¹Department of Neurology,The Ohio State University Wexner Medical Center ²Department of Physical Medicine and Rehabilitation,The Ohio State University ³Department of Neuroscience,The Ohio State University Wexner Medical Center ⁴Department of Biochemistry and Pharmacology,The Ohio State University Wexner Medical Center

Summary

Wir präsentieren raffinierten Protokolle, die in-vivo-Überwachung der Motoreinheit-Funktion in der Maus zu ermöglichen. Techniken zur Verbindung Muskelaktionspotential (CMAP) und Motoreinheit Nummer Schätzung (MUNE) in den Maus-Hinterbein Muskeln durch den Ischiasnerv innerviert messen, werden beschrieben.