Waiting
Login-Verarbeitung ...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Genetics / Ingeniør Kunstige Faktorer å Spesifikt Manipulere …
JoVE Journal
Genetics

Ein Abonnement für JoVE ist erforderlich, um diesen Inhalt ansehen zu können. Melden Sie sich an oder starten Sie Ihre kostenlose Testversion.

JoVE Journal Genetics
Ingeniør Kunstige Faktorer å Spesifikt Manipulere alternativ spleising i humane celler
Embryo Injections for CRISPR-Mediated Mutagenesis in the Ant Harpegnathos saltator
Journal (Genetics)
Embryo Injections for CRISPR-Mediated Mutagenesis in the Ant Harpegnathos saltator
Single-cell RNA Sequencing and Analysis of Human Pancreatic Islets
Journal (Genetics)
Single-cell RNA Sequencing and Analysis of Human Pancreatic Islets
 
Click here for the English version

Ingeniør Kunstige Faktorer å Spesifikt Manipulere alternativ spleising i humane celler

Article DOI: 10.3791/54967-v • 10:06 min • April 26th, 2017
April 26th, 2017 •
*1, *1, 2, 1, 1, 1, 1
1Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences (SIBS), 2Institute of Cancer Stem Cell, Second Affiliated Hospital, Cancer Center, Dalian Medical University
* These authors contributed equally

Kapitel

Summary
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

Denne rapporten beskriver en bioengineeringsmetode for å designe og konstruere nye kunstige spleisningsfaktorer (ASFs) som spesifikt modulerer spleising av målgener i pattedyrceller. Denne metoden kan utvides ytterligere til å konstruere ulike kunstige faktorer for å manipulere andre aspekter av RNA-metabolisme.

Tags

Genetikk utgave 122 kunstige RNA bindingsfaktorer protein engineering spleisningsfaktorer alternativ spleising PUF stillas RNA bindende proteiner kreft
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter