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Journal / Bioengineering / Nanosensors om te detecteren Protease activiteit…
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Bioengineering

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JoVE Journal Bioengineering
Nanosensors om te detecteren Protease activiteit In Vivo Noninvasive Diagnostics
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Nanosensors om te detecteren Protease activiteit In Vivo Noninvasive Diagnostics

Article DOI: 10.3791/57937-v • 10:50 min • July 16th, 2018
July 16th, 2018 •
1, 1, 1,2,3,4,5
1Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech College of Engineering and Emory School of Medicine, 2Parker H. Petit Institute of Bioengineering and Bioscience, 3Institute for Electronics and Nanotechnology, Georgia Tech, 4Integrated Cancer Research Center, Georgia Tech, 5The Georgia Immunoengineering Consortium, Emory University and Georgia Tech

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Proteasen zijn strak gereguleerde enzymen die betrokken zijn bij de fundamentele biologische processen en dysregulated protease-activiteit stations progressie van complexe ziekten zoals kanker. Doel van deze methode is het creëren van nanosensors die door het produceren van een decollete-signaal dat is aantoonbaar uit host urine en discrimineert ziekte protease activiteit in vivo meten.

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Bioengineering kwestie 137 synthetische biomarkers activity based sondes proteasen nanosensors nanodeeltjes urine diagnostiek
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