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Journal / Chemistry / 약물 약동 및 독성 평가를 위한 장/간 미생물학…
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Chemistry

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JoVE Journal Chemistry
약물 약동 및 독성 평가를 위한 장/간 미생물학 시스템
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약물 약동 및 독성 평가를 위한 장/간 미생물학 시스템

Article DOI: 10.3791/60184-v • 08:59 min • December 3rd, 2020
December 3rd, 2020 •
1, 4, 1, 1,2, 1, 1, 1, 3, 3, 1
1Brazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), 2Brazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy and Materials (CNPEM), 3Grupo Boticário, 4Institute of Biology, University of Campinas

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우리는 아세트아미노펜 (APAP)에 장과 간 오르가노이드를 가진 미생물 계통 (MPS)를 드러나. 이 문서에서는 MPS의 오르가노이드 생산 및 APAP 약동 및 독성 특성 평가를 위한 방법을 설명합니다. 또한 결과를 검증하는 데 필요한 조직 기능 분석을 설명합니다.

Tags

화학 문제 166 미생물 시스템 아세트 아미노펜 ADMETox 오르가노이드
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