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Immunology and Infection

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In Vivo Augmentation der Gut-Homing Regulatory T Cell Induction

Article DOI: 10.3791/60585-v • 08:02 min • January 22nd, 2020
January 22nd, 2020 •
1,2, 1, 1, 1,3,4, 1,3
1Division of Regenerative Medicine, Department of Medicine, Loma Linda University, 2Zhengzhou University, 3Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, Long Island University, 4Jinan Infectious Disease Hospital, Shandong University

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Hier stellen wir ein Protokoll zur In-vivo-Augmentation der Darmhoming-regulatorischen T-Zell-Induktion vor. In diesem Protokoll werden dendritische Zellen entwickelt, um lokal hohe Konzentrationen des aktiven Vitamin D (1,25-Dihydroxyvitamin D oder 1,25[OH]2D) und des aktiven VitaminS A (Retinoinsäure oder RA) de novo zu produzieren.

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Immunologie und Infektion Ausgabe 155 Darmhoming regulatorische T-Zellen 25-Hydroxyvitamin D 1-Hydroxylase Cytochrom P450 Familie 27 Unterfamilie B Mitglied 1 1,25-Dihydroxyvitamin D Foxp3 Dendritische Zellen Retinaldehyddehydrogenase 2 c-c Chemokin-Rezeptor Typ 9
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