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Journal / Chemistry / 18 F-Rotulagem de Radiotracers Funcionalizado com …
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Chemistry
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18 F-Rotulagem de Radiotracers Funcionalizado com um Acceptor de Fluoreto de Silício (SiFA) para Tomografia de Emissão de Pósitrons
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18 F-Rotulagem de Radiotracers Funcionalizado com um Acceptor de Fluoreto de Silício (SiFA) para Tomografia de Emissão de Pósitrons

Article DOI: 10.3791/60623-v • 09:57 min • January 11th, 2020
January 11th, 2020 •
*1, *1, 2,3, 2,3, 4, 5, 1, 1, 1
1Department of Oncology, University of Alberta, 2Department of Nuclear Medicine, University Hospital of Munich, 3ENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, LMU Munich, 4Biomedical Chemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University, 5Molecular Imaging and Radiochemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University
* These authors contributed equally

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A síntese de florina-18(18F) rotulada de radiofármacos para tomografia de emissão de pósitrons normalmente requer meses de experiência. Quando incorporado em um radiotracer, o motivo do acceptor do silicone-fluoreto (SiFA) permite um protocolo simples da 18F-etiquetagem que seja independente do equipamento caro e do treinamento preparatório, ao reduzir a quantidade do precursor necessário e a utilizar umas condições mais suaves da reação.

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Química Edição 155 18F-radiolabeling radiotracer imagem in vivo tomografia de emissão de pósitrons (PET) flúor-18 aceitador de silício-flúor (SiFA)
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