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Protocol for Developing a Femur Osteotomy Model in Wistar Albino Rats

Article DOI: 10.3791/63712-v • 05:43 min • August 31st, 2022
August 31st, 2022 •
1, 2, 2, 2, 2, 2, 2, 6, 6, 3, 4, 5, 1, 2
1Department of Orthopedics, All India Institute of Medical Sciences (AIIMS), 2Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), 3Department of Anaesthesiology Pain Medicine and Critical Care, All India Institute of Medical Sciences (AIIMS), 4Department of Radiodiagnosis, All India Institute of Medical Sciences (AIIMS), 5Department of Pathology, All India Institute of Medical Sciences (AIIMS), 6Central Council for Research in Homoeopathy (CCRH)

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Summary
Automatic Translation

Here, we present a protocol to iatrogenically fracture the shaft of the femur of Wistar albino rats and follow up on the development of the callus. This femur osteotomy model can help researchers evaluate the process of fracture healing and to study how a drug could influence fracture healing.

Tags

Femur Osteotomy Model Fracture Healing Drug Influence On Fracture Healing Bone-healing Properties Disease Pathogenesis Osteoanabolic Drugs Fracture Fixation Wax Block Sterile Drapes Skin Incision Vastus Lateralis Muscle Metzenbaum Scissors Periosteal Elevator Local Anesthesia
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