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JoVE Journal Cancer Research
Imaging PET/RM non invasivo in un modello murino ortotopico di carcinoma epatocellulare
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Imaging PET/RM non invasivo in un modello murino ortotopico di carcinoma epatocellulare

Article DOI: 10.3791/63958-v • 07:47 min • August 31st, 2022
August 31st, 2022 •
*1,2, *3, 2, 1, 4, 1,5, 3
1Department of Diagnostic Radiology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, 2Department of Oncology, MRC Oxford Institute for Radiation Oncology, University of Oxford, 3Department of Surgery, School of Clinical Medicine, HKU-SZH & LKS Faculty of Medicine, The University of Hong Kong, 4Department of Biomedical Engineering, The Chinese University of Hong Kong, 5Department of Diagnostic and Interventional Radiology, Kwong Wah Hospital
* These authors contributed equally

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Qui, presentiamo un protocollo per creare xenotrapianti di carcinoma epatocellulare ortotopico con e senza legatura dell'arteria epatica ed eseguire la tomografia ad emissione di positroni (PET) non invasiva dell'ipossia tumorale utilizzando [18 F]Fluoromisonidazolo ([18 F]FMISO) e [18 F]Fluorodesossiglucosio ([18F]FDG).

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