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Journal / Biology / 분자 모델링 접근법에 의한 Caspase 돌연변이 및 번역 후 변형…
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분자 모델링 접근법에 의한 Caspase 돌연변이 및 번역 후 변형 탐구

Article DOI: 10.3791/64206-v • 05:56 min • October 13th, 2022
October 13th, 2022 •
1, 2, 2,3, 2
1Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 2Faculty of Medicine, Lomonosov Moscow State University, 3Division of Toxicology, Institute of Environmental Medicine, Karolinska Institute

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본 프로토콜은 생체 분자 시뮬레이션 패키지를 사용하고 야생형 카스파제 및 그 돌연변이 형태를 모델링하기 위한 분자 역학(MD) 접근법을 설명합니다. MD 방법은 카스파제 구조의 동적 진화와 돌연변이 또는 번역 후 변형의 잠재적 효과를 평가할 수 있습니다.

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