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Journal / Bioengineering / 通过工程、条形码和筛选腺相关病毒 （AAV）…
JoVE Journal
Bioengineering

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JoVE Journal Bioengineering
通过工程、条形码和筛选腺相关病毒 （AAV） 衣壳变体分离下一代基因治疗载体
A Converging Strategy for the Generation of a Virtually Sequenced cDNA Library from Unreferenced Pacific Oysters
Journal (Bioengineering)
A Converging Strategy for the Generation of a Virtually Sequenced cDNA Library from Unreferenced Pacific Oysters
Automated Compression Testing of Porcine Ocular Lens and Estimation of the Lens Modulus (Video) | JoVE
Journal (Bioengineering)
Automated Compression Testing of Porcine Ocular Lens and Estimation of the Lens Modulus (Video) | JoVE
 
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通过工程、条形码和筛选腺相关病毒 （AAV） 衣壳变体分离下一代基因治疗载体

Article DOI: 10.3791/64389-v • 09:20 min • October 18th, 2022
October 18th, 2022 •
1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2,3,4,5
1Department of Infectious Diseases/Virology, Section Viral Vector Technologies, Medical Faculty, University of Heidelberg, 2BioQuant Center, BQ0030, University of Heidelberg, 3Cluster of Excellence CellNetworks, 4German Center for Infection Research (DZIF), 5German Center for Cardiovascular Research (DZHK)

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Summary
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AAV肽显示文库生成，随后通过条形码对具有新颖特性的候选物进行验证，以创建下一代AAV。

Tags

生物工程，第 188 期，AAV，AAV 文库，衣壳工程，基因治疗，高通量筛选，NGS，条形码文库
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