Christian Franke

Associate Professor
Christian Franke studied Physics at the University of Würzburg, where he also completed his PhD in the group of Markus Sauer, focusing on the development and application of super-resolution fluorescence microscopy. He subsequently joined the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in Dresden as a postdoctoral researcher in the laboratory of Marino Zerial, where he applied advanced imaging approaches to study intracellular membrane trafficking and endosomal organization. He is currently Professor of Digitized Experimental Microscopy at the Institute of Applied Optics and Biophysics (IAOB), Friedrich Schiller University Jena, Germany. His research focuses on the development of quantitative and computational optical methods that integrate optical engineering, super-resolution imaging, and data-driven analysis to investigate biological processes at nanometer resolution. His team develops new approaches for quantitative super-resolution microscopy, computational multiplexing, and high-throughput image analysis. These technologies are applied to study intracellular organization, nanoparticle uptake and trafficking, and endo-lysosomal biology, often in close collaboration with researchers in cell biology, photonics, and biomedical sciences. His work aims to translate advanced optical and computational imaging technologies into robust tools for quantitative cell biology and biomedical research.