Edwin Roger Parra Department of Translational Molecular Pathology The University of Texas MD Anderson Cancer Center Biography Publications Institution JoVE Articles Edwin Roger Parra has not added a biography. If you are Edwin Roger Parra and would like to personalize this page please email our Author Liaison for assistance. Publications Editorial: Multiplexed Image Analysis for Translational Research Project Applications Frontiers in Oncology. 2022 | Pubmed ID: 36465347 Immunogenomic Profiling of Lung Adenocarcinoma Reveals Poorly Differentiated Tumors Are Associated with an Immunogenic Tumor Microenvironment Lung Cancer (Amsterdam, Netherlands). Oct, 2022 | Pubmed ID: 35973335 Durvalumab Plus Tremelimumab in Advanced or Metastatic Soft Tissue and Bone Sarcomas: a Single-centre Phase 2 Trial The Lancet. Oncology. Sep, 2022 | Pubmed ID: 35934010 Multiplex Immunofluorescence and the Digital Image Analysis Workflow for Evaluation of the Tumor Immune Environment in Translational Research Frontiers in Oncology. 2022 | Pubmed ID: 35832550 Pathological Response and Immune Biomarker Assessment in Non-Small-Cell Lung Carcinoma Receiving Neoadjuvant Immune Checkpoint Inhibitors Cancers. Jun, 2022 | Pubmed ID: 35681755 Impact of Region-of-Interest Size on Immune Profiling Using Multiplex Immunofluorescence Tyramide Signal Amplification for Paraffin-Embedded Tumor Tissues Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. May, 2022 | Pubmed ID: 35609532 Effector Memory Cytotoxic CD3/CD8/CD45RO T Cells Are Predictive of Good Survival and a Lower Risk of Recurrence in Triple-negative Breast Cancer Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Nov, 2021 | Pubmed ID: 34839351 Cold and Heterogeneous T Cell Repertoire is Associated with Copy Number Aberrations and Loss of Immune Genes in Small-cell Lung Cancer Nature Communications. 11, 2021 | Pubmed ID: 34789716 Single Cell T Cell Landscape and T Cell Receptor Repertoire Profiling of AML in Context of PD-1 Blockade Therapy Nature Communications. 10, 2021 | Pubmed ID: 34663807 Best Practices for Technical Reproducibility Assessment of Multiplex Immunofluorescence Frontiers in Molecular Biosciences. 2021 | Pubmed ID: 34532339 Pathology Quality Control for Multiplex Immunofluorescence and Image Analysis Assessment in Longitudinal Studies Frontiers in Molecular Biosciences. 2021 | Pubmed ID: 34395517 A Proteogenomic Portrait of Lung Squamous Cell Carcinoma Cell. 08, 2021 | Pubmed ID: 34358469 Methods to Determine and Analyze the Cellular Spatial Distribution Extracted From Multiplex Immunofluorescence Data to Understand the Tumor Microenvironment Frontiers in Molecular Biosciences. 2021 | Pubmed ID: 34179080 Multiplex Immunofluorescence Tyramide Signal Amplification for Immune Cell Profiling of Paraffin-Embedded Tumor Tissues Frontiers in Molecular Biosciences. 2021 | Pubmed ID: 33996912 Author Correction: Multi-region Exome Sequencing Reveals Genomic Evolution from Preneoplasia to Lung Adenocarcinoma Nature Communications. May, 2021 | Pubmed ID: 33980839 Contextual Cues from Cancer Cells Govern Cancer-associated Fibroblast Heterogeneity Cell Reports. 04, 2021 | Pubmed ID: 33882319 Immuno-profiling and Cellular Spatial Analysis Using Five Immune Oncology Multiplex Immunofluorescence Panels for Paraffin Tumor Tissue Scientific Reports. 04, 2021 | Pubmed ID: 33875760 Pilot Clinical Trial of Perioperative Durvalumab and Tremelimumab in the Treatment of Resectable Colorectal Cancer Liver Metastases Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 06, 2021 | Pubmed ID: 33811152 Case Report: Enfortumab Vedotin for Metastatic Urothelial Carcinoma: A Case Series on the Clinical and Histopathologic Spectrum of Adverse Cutaneous Reactions From Fatal Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis to Dermal Hypersensitivity Reaction Frontiers in Oncology. 2021 | Pubmed ID: 33747934 Western Blot As a Support Technique for Immunohistochemistry to Detect Programmed Cell Death Ligand 1 Expression Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 33683685 Detection of Programmed Cell Death Ligand 1 Expression in Lung Cancer Clinical Samples by an Automated Immunohistochemistry System Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 33683684 Identification of Distinct Immune Landscapes Using an Automated Nine-color Multiplex Immunofluorescence Staining Panel and Image Analysis in Paraffin Tumor Tissues Scientific Reports. 02, 2021 | Pubmed ID: 33633208 Multi-omic Molecular Profiling Reveals Potentially Targetable Abnormalities Shared Across Multiple Histologies of Brain Metastasis Acta Neuropathologica. 02, 2021 | Pubmed ID: 33394124 Variants in Epithelial-Mesenchymal Transition and Immune Checkpoint Genes Are Associated With Immune Cell Profiles and Predict Survival in Non-Small Cell Lung Cancer Archives of Pathology & Laboratory Medicine. 10, 2020 | Pubmed ID: 32150457 Comprehensive T Cell Repertoire Characterization of Non-small Cell Lung Cancer Nature Communications. 01, 2020 | Pubmed ID: 32001676 Procedural Requirements and Recommendations for Multiplex Immunofluorescence Tyramide Signal Amplification Assays to Support Translational Oncology Studies Cancers. Jan, 2020 | Pubmed ID: 31972974 Multiplex Immunofluorescence Assays Methods in Molecular Biology (Clifton, N.J.). 2020 | Pubmed ID: 31502166 Multi-region Exome Sequencing Reveals Genomic Evolution from Preneoplasia to Lung Adenocarcinoma Nature Communications. 07, 2019 | Pubmed ID: 31278276 Targeting the Interplay Between Epithelial-to-Mesenchymal-Transition and the Immune System for Effective Immunotherapy Cancers. May, 2019 | Pubmed ID: 31137625 B7-H3 Expression in Merkel Cell Carcinoma-Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 06, 2019 | Pubmed ID: 30808776 State-of-the-Art of Profiling Immune Contexture in the Era of Multiplexed Staining and Digital Analysis to Study Paraffin Tumor Tissues Cancers. Feb, 2019 | Pubmed ID: 30791580 Usefulness of Complementary Next-generation Sequencing and Quantitative Immunohistochemistry Panels for Predicting Brain Metastases and Selecting Treatment Outcomes of Non-small Cell Lung Cancer Human Pathology. 01, 2019 | Pubmed ID: 30218756 Histomorphometric Evaluation of the Ki-67 Proliferation Rate and CD34 Microvascular and D2-40 Lymphovascular Densities Drives the Pulmonary Typical Carcinoid Outcome Human Pathology. 11, 2018 | Pubmed ID: 30031097 A Functional Spatial Analysis Platform for Discovery of Immunological Interactions Predictive of Low-Grade to High-Grade Transition of Pancreatic Intraductal Papillary Mucinous Neoplasms Cancer Informatics. 2018 | Pubmed ID: 30013304 Effect of Neoadjuvant Chemotherapy on the Immune Microenvironment in Non-small Cell Lung Carcinomas As Determined by Multiplex Immunofluorescence and Image Analysis Approaches Journal for Immunotherapy of Cancer. Jun, 2018 | Pubmed ID: 29871672 Immunohistochemical and Image Analysis-Based Study Shows That Several Immune Checkpoints Are Co-expressed in Non-Small Cell Lung Carcinoma Tumors Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. 06, 2018 | Pubmed ID: 29526824 Validation of Multiplex Immunofluorescence Panels Using Multispectral Microscopy for Immune-profiling of Formalin-fixed and Paraffin-embedded Human Tumor Tissues Scientific Reports. Oct, 2017 | Pubmed ID: 29042640 4-1BB Agonist Focuses CD8(+) Tumor-Infiltrating T-Cell Growth into a Distinct Repertoire Capable of Tumor Recognition in Pancreatic Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2017 | Pubmed ID: 28947567 Multiplexed Barcoding Image Analysis for Immunoprofiling and Spatial Mapping Characterization in the Single-Cell Analysis of Paraffin Tissue Samples Saxon Rodriguez*1, Baohua Sun*1, Salome McAllen1, Mei Jiang1, Edwin Roger Parra1 1Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center JoVE 64758 Investigación sobre el cáncer Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples Leticia Campos Clemente1, Ou Shi1, Frank Rojas1, Edwin Roger Parra1 1Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center JoVE 64015 Investigación sobre el cáncer
Multiplexed Barcoding Image Analysis for Immunoprofiling and Spatial Mapping Characterization in the Single-Cell Analysis of Paraffin Tissue Samples Saxon Rodriguez*1, Baohua Sun*1, Salome McAllen1, Mei Jiang1, Edwin Roger Parra1 1Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center JoVE 64758 Investigación sobre el cáncer
Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples Leticia Campos Clemente1, Ou Shi1, Frank Rojas1, Edwin Roger Parra1 1Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center JoVE 64015 Investigación sobre el cáncer
