Microwave Irradiation

Microwave irradiation is the application of electromagnetic radiation in the microwave frequency range to transfer energy rapidly into materials, making it a useful heating and processing method in bioengineering. Its mechanism depends on dielectric heating: oscillating electric fields induce polar molecules and mobile ions to rotate or move, converting electromagnetic energy into heat within the material. Unlike conventional surface heating, this volumetric energy transfer can shorten processing times and alter temperature profiles, although absorption depends on composition, moisture, geometry, and frequency. In bioengineering, microwave irradiation supports sample preparation, biomaterial and polymer processing, assisted synthesis, and controlled treatment of biological materials, with potential to improve efficiency and reproducibility when exposure conditions are carefully optimized.

Microwave Irradiation - Related Videos

Research

JoVE Journal - Chemistry

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation

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Cited by 10 •

2016

A simple and general method for the synthesis of cyclic peptides using microwave irradiation is outlined. This procedure enables the synthesis of backbone cyclic peptides with a collection of different conformations while retaining the side chains and the pharmacophoric moieties., and therefore, allows to screen for the bioactive conformation.

Research

JoVE Journal - Chemistry
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Non-equilibrium Microwave Plasma for Efficient High Temperature Chemistry

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Cited by 8 •

2017

This article describes a flowing microwave reactor that is used to drive efficient non-equilibrium chemistry for the application of conversion/activation of stable molecules such as CO2, N2 and CH4. The goal of the procedure described here is to measure the in situ gas temperature and gas conversion.

A Mouse Model of Fatigue Induced by Peripheral Irradiation

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Cited by 18 •

2017

We describe a method using targeted peripheral irradiation to induce fatigue-like behavior in mice. The selected non-lethal irradiation dose leads to a week-long reduction in voluntary wheel-running activity.

Planarian Immobilization, Partial Irradiation, and Tissue Transplantation

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Cited by 20 •

2012

An effective method for grafting tissue of defined and consistent size between planaria is described. Also included is a description of how the immobilization technique used for transplantation can be adapted, in conjunction with lead shields, for the partial irradiation of live animals.

UV Irradiation: A Method to Integrate Extrachromosomal Arrays

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2023

Microinjection of transgenes usually results in C. elegans strains with large extrachromosomal arrays, which result in variable expression and transmission of the transgene. UV Irradiation can induce chromosomal integration of the array and more stable transgene transmission.

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