Twin-screw Reactor

A twin-screw reactor is a continuous processing device that uses two intermeshing, rotating screws to transport, mix, and transform materials under controlled conditions. As the screws rotate within a heated or cooled barrel, their geometry produces distributive mixing, dispersive shear, and controlled residence time while enabling heat and mass transfer. In bioengineering, twin-screw reactors support the processing of polymers, biomaterials, pharmaceutical formulations, and other sensitive materials, often combining blending, reaction, and shaping in one operation. Their continuous design can improve process consistency, scalability, and control compared with batch methods, supporting advances in drug delivery, tissue engineering, and biomanufacturing.

Twin-screw Reactor - Related Videos

Research

JoVE Journal - Bioengineering
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Fast Pyrolysis of Biomass Residues in a Twin-screw Mixing Reactor

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Cited by 20 •

2016

A procedure for thermochemical conversion of biomass residues is presented that aims at maximizing the yield of liquid products (fast pyrolysis). It is based on a technology proven on an industrial scale and especially suitable for treating a straw type of biomass.

Research

JoVE Journal - Engineering

Twin-Screw Extrusion Process to Produce Renewable Fiberboards

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Cited by 14 •

2021

A versatile twin-screw extrusion process to provide an efficient thermo-mechano-chemical pretreatment on lignocellulosic biomass was developed, which leads to an increased average fiber aspect ratio. A natural binder can also be added continuously after fiber refining, leading to bio-based fiberboards with improved mechanical properties after hot pressing of the obtained extruded material.

Education

JoVE Science Education - Basic Biology

Operation of High-pressure Reactor Vessels

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2023

Robert M Rioux, Pennsylvania State University, University Park, PA The use of gases in a synthetic chemistry laboratory is essential for carrying out a variety of highly facile and atom economical transformations. Reactions such as hydrogenation, oxidation, and amination require the use of gases like hydrogen, oxygen, and ammonia. Due to the poor solubility of these gases in typical reactant solutions, high pressures are necessary to achieve a meaningful reaction rate. Not only are these gases...

Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization

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2015

A protocol for the high-throughput analysis of polymerization catalyst, chain transfer polymerizations, polyethylene characterization, and reaction kinetic analysis is presented.

Catalytic Reactor: Hydrogenation of Ethylene

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2023

Source: Kerry M. Dooley and Michael G. Benton, Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA The hydrogenation of ethylene (C2H4) to ethane (C2H6) has often been studied as a model reduction reaction in characterizing new metal catalysts.1-2 While supported nickel is not the most active metal catalyst for this reaction, it is active enough that reaction can take place at < 200°C. The reaction typically involves adsorbed, dissociated hydrogen (H2) reacting...

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