Magnetic Plate Washer

A magnetic plate washer is a laboratory instrument that automates the separation and washing of magnetic bead-based assays in multiwell plates, improving consistency while reducing manual handling. During each cycle, a magnetic field immobilizes beads and their bound targets against the well surface or a collection area while liquid is aspirated, replaced with wash buffer, and removed without disturbing the retained material. In immunology and infection research, this process supports antibody and antigen assays, nucleic-acid purification, and pathogen-detection workflows by reducing carryover and background signal. Standardized washing can improve reproducibility, throughput, and analytical reliability across research and diagnostic settings.

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Research

JoVE Journal - Bioengineering
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Metabolic Support of Excised, Living Brain Tissues During Magnetic Resonance Microscopy Acquisition

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Cited by 2 •

2017

The current protocol describes a method by which users can maintain viability of acute hippocampal and cortical slice preparations during the collection of magnetic resonance microscopy data.

Education

JoVE Science Education - Physics

Magnetic Fields

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2023

Source: Yong P. Chen, PhD, Department of Physics & Astronomy, College of Science, Purdue University, West Lafayette, IN Magnetic fields can be generated by moving charges, such as an electrical current. The magnetic field generated by a current can be calculated from the Maxwell equation. In addition, magnetic objects such as bar magnets can also generate magnetic fields due to microscopic dynamics of charges inside the material. Magnetic fields will exert magnetic force on other moving...

Evaporation-reducing Culture Condition Increases the Reproducibility of Multicellular Spheroid Formation in Microtiter Plates

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Cited by 6 •

2017

The uneven loss of medium from microtiter plates affects the reproducibility of uniform multicellular tumor spheroid formation. Improving culture conditions to reduce significant medium loss will improve the reproducibility of spheroid formation and the results of spheroid-based assays using the liquid-overlay technique.

Colors and Magnetism

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2020

Color in Coordination Complexes When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human eye.

Characterization of Magnetic Components

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2023

Source: Ali Bazzi, Department of Electrical Engineering, University of Connecticut, Storrs, CT. The objective of this experiment is to achieve hands-on experience with different magnetic components from design and material perspectives. This experiment covers B-H curves of magnetic material and inductor design through identifying unknown design factors. The B-H curve of a magnetic element, such as an inductor or transformer, is a characteristic of the magnetic material forming the core around...

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