Gastroenterology
Gastroenterology - Related Videos
10:29
Simulating Pancreatic Neuroplasticity: In Vitro Dual-neuron Plasticity Assay
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Cited by 3 •
2014
Neuronal plasticity is an increasingly recognized, but insufficiently understood feature of the gastrointestinal (GI) tract. Here, in the example of human pancreatic disorders, we present an in vitro neuroplasticity assay for the study of neuronal plasticity in the GI tract at both morphological and functional level.
06:38
A Novel Method for the Culture and Polarized Stimulation of Human Intestinal Mucosa Explants
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Cited by 16 •
2013
We introduce a novel method for the maintenance of human intestinal mucosa in culture and monitoring of the response to various types of stimuli over at least 24 hrs. With our method, the polarity of the tissue is maintained, allowing for a physiological stimulation via the apical route.
07:07
Murine Model of Intestinal Ischemia-reperfusion Injury
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Cited by 52 •
2016
Here we describe the detailed procedure of intestinal ischemia-reperfusion in mice which results in reproducible injury without mortality to encourage the standardization of this technique across the field. This model of intestinal ischemia-reperfusion injury can be utilized to study the cellular and molecular mechanisms of injury and regeneration.
08:22
Isolation and Characterization of Mouse Primary Liver Sinusoidal Endothelial Cells
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Cited by 6 •
2021
Here we outline and demonstrate a protocol for primary mouse liver sinusoidal endothelial cell (LSEC) isolation. The protocol is based on liver collagenase perfusion, nonparenchymal cell purification by low-speed centrifugation, and CD146 magnetic bead selection. We also phenotype and characterize these isolated LSECs using flow cytometry and scanning electron microscopy.
06:28
E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
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Cited by 3 •
2019
The aim of this trial is to establish the position of online computer-based education as a tool for patient preparation prior to a colonoscopy. Computer based education is compared with the standard of care, nurse counseling, evaluating endoscopic quality measures and patient related outcome measures.
FAQs
Diagnosis typically proceeds by combining the patient’s history and physical examination with targeted tests. Laboratory studies can assess abnormalities, while imaging and endoscopy help visualize structures and identify inflammation, infection, obstruction, or bleeding. Tissue analysis adds cellular information when an abnormality requires further characterization for clinical interpretation.
Different digestive organs contribute to distinct but connected functions. The gastrointestinal tract supports digestion and nutrient absorption, while the liver, gallbladder, and pancreas are evaluated in relation to digestion and metabolism. Because disorders may affect more than one component, gastroenterology considers these structures as an integrated system rather than interpreting symptoms in isolation.
Each diagnostic modality contributes a different type of evidence. Patient history and physical examination establish clinical context, laboratory tests provide measurable findings, imaging and endoscopy help assess internal structures, and tissue analysis examines sampled material. Using these sources together can distinguish patterns such as inflammation, infection, obstruction, bleeding, or abnormal organ function more reliably than relying on one source alone.
Digestive health extends beyond the movement of food through the gastrointestinal tract. Problems affecting digestion, nutrient absorption, or metabolism can have consequences for overall human health, which is why the specialty includes disorders involving the liver, gallbladder, and pancreas as well as the gastrointestinal tract. This systems perspective connects local digestive findings with broader medical assessment.
An evaluation generally begins with patient history and physical examination. Clinicians then select laboratory tests, imaging, endoscopy, or tissue analysis according to the findings they need to investigate. This staged combination helps organize information about inflammation, infection, obstruction, bleeding, or abnormal organ function and supports decisions about diagnosis and treatment.
When internal abnormalities require closer investigation, imaging or endoscopy can add structural information to the initial clinical assessment. If tissue analysis is also needed, it provides another layer of evidence for characterizing an abnormality. Together, these approaches help clinicians investigate suspected disease processes while connecting visible or measurable findings with the patient’s clinical presentation.
Gastroenterology supports more than treatment of established disease. Its advances contribute to screening, minimally invasive treatment, disease prevention, and improved understanding of how digestive health influences overall human health. These applications span conditions affecting the gastrointestinal tract, liver, gallbladder, or pancreas, linking specialty-specific care with broader medical goals.