Right Ventricular Apex
Right Ventricular Apex - Related Videos
03:58
Apical Resection Neonatal Mouse Model: A Surgical Procedure to Amputate the Ventricular Apex to Study Regenerative Potential in a Neonate Mouse Heart
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2025
In this video, we demonstrate the procedure to surgically remove the left ventricular apex of a neonatal mouse heart.
07:51
Murine Short Axis Ventricular Heart Slices for Electrophysiological Studies
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Cited by 3 •
2017
Here, we describe the preparation of viable ventricular slices from adult mice and their use for sharp electrode action potential recordings. These multicellular preparations provide a preserved in vivo like tissue structure, which makes them a valuable model for electrophysiological and pharmacological studies in vitro.
07:24
Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR
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Cited by 34 •
2013
This article describes procedures for implanting a novel hydrogel in failing hearts and quantifying its effect on left ventricular wall stress and function. These procedures have been successfully applied in dogs and humans.
08:15
Measuring Left Ventricular Pressure in Late Embryonic and Neonatal Mice
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Cited by 18 •
2012
Measuring left ventricular pressure (LV) in embryonic and neonatal mice is described. Pressure is measured by inserting a needle connected to a fluid-filled transducer into the LV under ultrasound guidance. Care must be taken to maintain normal cardiac function during the experimental protocol.
09:22
Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
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Cited by 22 •
2015
Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and Right Ventricular (RV) dysfunction were induced in piglets by progressive obstruction of the pulmonary arteries. Consequences were remarkably similar to those observed in CTEPH patients. This animal model would be a very useful tool for pathophysiology and therapeutic experiments on CTEPH and RV failure.
FAQs
During ventricular systole, myocardial fibers and trabeculae in the right ventricular apex contract with the ventricular wall. This coordinated contraction contributes to moving blood toward the pulmonary valve, rather than treating the apex as an isolated structure. Its mechanical contribution therefore belongs to the broader pumping action of the right ventricle and supports efficient right-sided circulation.
Assessment of regional wall motion at the apex provides information about how this segment participates in right ventricular contraction. Clinicians interpret that motion alongside chamber function and structural findings, because a regional observation does not stand alone in evaluating the ventricle. This combined assessment is relevant when investigating right ventricular failure, pulmonary hypertension, congenital heart disease, or selected cardiomyopathies.
Myocardial fibers and trabeculae provide contractile structures within the right ventricular apex. During systole, their activity is coordinated with contraction of the ventricular wall, helping direct blood toward the pulmonary valve. Examining this organized movement allows clinicians to relate local apex behavior to overall right ventricular chamber function and to the efficiency of right-sided circulation.
Clinicians use echocardiography to examine right ventricular apex movement as part of regional wall motion assessment. The study can also contribute information about overall chamber function and structural abnormalities. This makes the apex useful for a focused look at contraction while retaining the broader context needed to evaluate right-sided cardiac performance.
Cardiac magnetic resonance imaging provides another way to assess the right ventricular apex, including regional wall motion, chamber function, and structural abnormalities. Its role is useful when clinicians need imaging information about the right ventricle in the context of suspected right ventricular failure, pulmonary hypertension, congenital heart disease, or selected cardiomyopathies.
The appearance or movement of the right ventricular apex can aid clinical assessment across several disease contexts, including right ventricular failure, pulmonary hypertension, congenital heart disease, and selected cardiomyopathies. In practice, clinicians consider these observations as part of evaluating regional wall motion, chamber function, and structural abnormalities, allowing the apex to contribute focused information without replacing broader cardiac assessment.