Single Port Nephrectomy

Single-port nephrectomy is a minimally invasive operation that removes one kidney through a single small incision, offering an alternative to open or multiport surgery. Surgeons insert a camera and specialized instruments through a multichannel port, create abdominal working space with carbon dioxide, and carefully isolate, seal, and divide the renal blood vessels and ureter before extracting the kidney. The technique can treat kidney tumors, severe nonfunctioning kidneys, and selected living-donor cases. By limiting access to one incision, it may reduce abdominal scarring while preserving the precision of laparoscopic or robotic visualization and instrument control.

Single Port Nephrectomy - Related Videos

Research

JoVE Journal - Medicine
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Single Port Donor Nephrectomy

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Cited by 5 •

2011

Single port laparoscopic surgery is changing the standard of care in surgical care like nothing since the laparoscopic technique was introduced 20 years ago. We present out technique of single port donor nephrectomy using the Gelpoint device. We have successfully performed this surgery in 100 patients.

Research

JoVE Journal - Biology

A Mouse 5/6th Nephrectomy Model That Induces Experimental Uremic Cardiomyopathy

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Cited by 41 •

2017

This manuscript provides a detailed two-step surgical procedure to perform mouse 5/6th partial nephrectomy (PNx) with pole ligation. Four weeks after surgery, in comparison with sham-operated mice, the PNx mice developed impaired renal function, anemia, cardiac hypertrophy, cardiac fibrosis, and decreased heart systolic and diastolic function.

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy

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Cited by 23 •

2014

Models of spontaneous metastatic renal cell carcinoma (RCC) disease progression can be used for evaluating treatments in a clinically relevant setting. This protocol demonstrates different procedures for orthotopic kidney tumor cell implantation, proper nephrectomy, and finally outlines a necropsy guide for visual and bioluminescent scoring of metastatic burden and localization.

Single-port Robotic Transanal Total Mesorectal Excision in a Porcine Model (Sus scrofa domesticus)

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2026

This protocol demonstrates Single-port (SP) robotic transanal total mesorectal excision (taTME) in a porcine model, highlighting procedural feasibility, technical steps, and preclinical applicability for minimally invasive rectal surgery.

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial

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2025

This prospective study evaluated the implementation of a novel, single-port, robotic platform in oncoplastic breast-conserving surgery for malignant lesions. The primary endpoint focused on technical success, defined as the achievement of tumor-free resection margins confirmed by intraoperative frozen-section histopathology, with secondary assessment of aesthetic outcomes and life quality score of patients.

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