Microliter Syringe

A microliter syringe is a precision instrument designed to measure and deliver very small liquid volumes, typically at the microliter scale, with accuracy that supports controlled laboratory experiments. It uses a calibrated barrel, low-dead-volume plunger, and fine needle to create and dispense a defined volume while minimizing leakage, evaporation, and sample loss. In neuroscience, researchers use microliter syringes to administer drugs, tracers, or other solutions into targeted tissues, prepare samples for analysis, and support microinjection or infusion procedures. Their precision improves dose control, experimental reproducibility, and the study of neural circuits, pharmacological responses, and brain function.

Microliter Syringe - Related Videos

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JoVE EoE - Bacterial Growth and Techniques

Extraction of Apoplastic Bacteria Using a Syringe-Based Pressure Method

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2025

Source: Rufián, J. S., et al, Single-Cell Analysis of the Expression of Pseudomonas syringae Genes within the Plant Tissue. J. Vis. Exp. (2022)This video demonstrates a syringe-based pressure method for extracting apoplastic bacteria, which proliferate and form microcolonies within the apoplast, the intercellular space between plant cells. The method yields debris-free bacterial samples suitable for downstream single-cell analysis.

Research

JoVE Journal - Bioengineering
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Syringe-injectable Mesh Electronics for Stable Chronic Rodent Electrophysiology

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Cited by 29 •

2018

Mesh electronics probes seamlessly integrate and provide stable, long-term, single-neuron level recording within the brain. This protocol uses mesh electronics for in vivo experiments, involving the fabrication of mesh electronics, loading into needles, stereotaxic injection, input/output interfacing, recording experiments, and histology of tissue containing mesh probes.

Research

JoVE Journal - Cancer Research

Modeling the Effects of Hemodynamic Stress on Circulating Tumor Cells using a Syringe and Needle

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Cited by 2 •

2021

Here we demonstrate a method to apply fluid shear stress to cancer cells in suspension to model the effects of hemodynamic stress on circulating tumor cells.

Measuring Outflow Facility And Ocular Compliance In Ex Vivo Mouse Eyes Using A Syringe-pump System

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2026

Integrating analytical approaches from established pressure-controlled perfusion methods optimized a simple, low-cost syringe-pump system for assessing outflow facility and ocular compliance in mouse eyes.

Automated and High-throughput Microbial Monoclonal Cultivation and Picking Using the Single-cell Microliter-droplet Culture Omics System

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2025

This protocol describes how to use the Single-cell Microliter-droplet Culture Omics System (MISS cell) to perform microbial monoclonal isolation, cultivation, and picking. The MISS cell achieves an integrated workflow based on droplet microfluidic technology, which offers excellent droplet monodispersity, high parallel cultivation, and high-throughput biomass detection.

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