Sensor Digitization

Sensor digitization is the process of converting continuous physical signals from sensors into discrete digital data for storage, analysis, and transmission. In neuroscience, an analog-to-digital converter samples signals such as electrical activity from neurons or brain regions at defined time intervals, assigns each measurement a finite numerical value through quantization, and encodes the results for computational processing. Sampling rate, resolution, input range, and electrical noise determine how accurately the digital record represents the original signal and whether rapid neural events can be distinguished. These data support electrophysiological recording, EEG, and neural-interface systems, enabling filtering, feature extraction, visualization, and quantitative comparison across experiments.

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Education

JoVE Science Education - Chemistry

Glovebox and Impurity Sensors

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2023

Source: Tamara M. Powers, Department of Chemistry, Texas A&M University The glovebox provides a straightforward means to handle air- and moisture-sensitive solids and liquids. The glovebox is what it sounds like: a box with gloves attached to one or more sides, which allows the user to perform manipulations within the glovebox under an inert atmosphere. For manipulations under inert atmospheres, chemists can choose between Schlenk or high-vacuum techniques and a glovebox. Schlenk and...

Research

JoVE Journal - Medicine
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Use of a Low-flow Digital Anesthesia System for Mice and Rats

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Cited by 4 •

2016

Here, we present a protocol to more safely and efficiently administer anesthetic gas to mice using a digital, low flow anesthesia system utilizing a syringe-driven direct injection vaporizer.

Bacterial Detection & Identification Using Electrochemical Sensors

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Cited by 6 •

2013

We describe an electrochemical sensor assay method for rapid bacterial detection and identification. The assay involves a sensor array functionalized with DNA oligonucleotide capture probes for ribosomal RNA (rRNA) species-specific sequences. Sandwich hybridization of target rRNA with the capture probe and a horseradish peroxidase-linked DNA oligonucleotide detector probe produces a measurable amperometric current.

Glutamine Flux Imaging Using Genetically Encoded Sensors

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Cited by 7 •

2014

This article will demonstrate how to monitor glutamine dynamics in live cells using FRET. Genetically encoded sensors allow real-time monitoring of biological molecules at a subcellular resolution. Experimental design, technical details of the experimental settings, and considerations for post-experimental analyses will be discussed for genetically encoded glutamine sensors.

Measuring Engagement of Spectators of Social Digital Games

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2021

We propose a methodology that enables measuring engagement of spectators in a social digital game combining physiological and self-reported data. As this digital game involves a group of freely moving people, the experience is filmed using a synchronizing technique that links physiological data with events in the game.

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