Somatosensory Axons

Somatosensory axons are nerve-cell projections that transmit information about touch, pressure, temperature, pain, and body position from peripheral receptors to the central nervous system. When sensory receptors are activated, these axons convert the stimulus into action potentials, which travel along their membranes and enter the spinal cord or brain through organized neural pathways; myelination can increase conduction speed. Studying somatosensory axons helps explain how the nervous system encodes and localizes bodily sensations, including signals carried by distinct fiber types. Their structure and function are central to research on pain, tactile perception, proprioception, nerve injury, and sensory rehabilitation.

Somatosensory Axons - Related Videos

Research

JoVE Journal - Neuroscience

Somatosensory Event-related Potentials from Orofacial Skin Stretch Stimulation

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Cited by 4 •

2015

This paper introduces a method for obtaining somatosensory event-related potentials following orofacial skin stretch stimulation. The current method can be used to evaluate the contribution of somatosensory afferents to both speech production and speech perception.

Obtaining Somatosensory Stimulation-Related Signals from Orofacial Skin Stretching

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2025

This video demonstrates the recording of somatosensory stimulation-related signals through orofacial skin stretch using an electroencephalography (EEG) cap equipped with electrodes to monitor brain activity and a robotic device that produces the skin stretch.

Intravital Two-Photon Imaging of Touch Sensory Axon Morphology in Mouse Skin

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2025

This study presents an in vivo two-photon imaging approach for visualizing the structures of low-threshold mechanoreceptor (LTMR) axon terminals in the forepaw skin of mice. Using repeated, high-resolution imaging of individual axons, this method provides a new platform for studying the structure and function of the cutaneous sensory circuit during development and in adults.

Optogenetic Activation of Zebrafish Somatosensory Neurons using ChEF-tdTomato

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Cited by 6 •

2013

Optogenetic techniques have made it possible to study the contribution of specific neurons to behavior. We describe a method in larval zebrafish for activating single somatosensory neurons expressing a channelrhodopsin variant (ChEF) with a diode-pumped solid state (DPSS) laser and recording the elicited behaviors with a high-speed video camera.

Two-Photon Laser Axotomy: A Method to Injure Axons in Zebrafish Embryos and Observe Axonal Recovery

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2023

This video describes the method to injure axons in zebrafish embryos using two photon laser axotomy and observing axonal recovery from injury.

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