Visual Pathway

The visual pathway is the network of neural structures that carries and processes information from the retina to the brain, enabling visual perception and guiding behavior. Light-evoked signals travel through retinal ganglion cells and the optic nerve, partially cross at the optic chiasm, and continue through the optic tract to the lateral geniculate nucleus before reaching the primary visual cortex through optic radiations. Additional projections support eye movements, reflexes, and spatial orientation. Studying this pathway helps explain how the brain represents visual features and allows researchers and clinicians to predict the effects of lesions, developmental abnormalities, and neurological disease.

Visual Pathway - Related Videos

Education

JoVE Core - Anatomy and Physiology

Photoreceptors and Visual Pathways

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2025

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

Research

JoVE EoE - Neurophysiology

Visualization and Mapping of Neuronal Pathways in an Amygdala Brain Slice

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2025

This video demonstrates a procedure for analyzing synaptic connectivity between medial prefrontal cortex (mPFC) and amygdala neurons using acute amygdala brain slices from mice. The mPFC neurons in these mice express channelrhodopsin fused to a fluorescent protein. The channelrhodopsins facilitate ion influx and action potential generation in the mPFC neurons upon light activation. Consequently, mPFC neurons release neurotransmitters that bind to postsynaptic amygdala neurons, triggering...

Preparing a Rat Model to Assess Visual Pathway Integrity Using an Electrophysiology Setup

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2025

This video demonstrates the preparation of a rat model to study retinal health and visual pathway integrity. Visual evoked potential and electroretinography reference and active electrodes are connected to the rat, followed by aligning the platform with the rat in front of the Ganzfeld bowl for even retinal illumination and closing the Faraday cage to avoid external interference.

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

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Cited by 5 •

2016

This manuscript describes deterministic and probabilistic algorithms for white matter (WM) reconstruction, used to examine differences in optic radiation (OR) connectivity between albinism and controls. Although probabilistic tractography follows the true course of nerve fibers more closely, deterministic tractography was run to compare the reliability and reproducibility of both techniques.

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

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Cited by 13 •

2014

Diffusion tensor imaging (DTI) was performed to try to depict the major parts of the visual pathway. The goal was to use an FDA approved standard commercial workstation which could be used for everyday routine in order to try to reduce postoperative damage of the visual pathway in the patients.

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