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Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
DOI:

13:26 min

August 11, 2016

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Chapters

  • 00:05Title
  • 00:51Subject Preparation & Structural MRI Parameters
  • 02:55LGN Delineation
  • 03:58V1 Segmentation and Pre-tracking Registrations
  • 07:32Probabilistic Tractography
  • 08:53Deterministic Tractography (DSI Studios)
  • 10:13Results: Deterministic and Probabilistic Tractography in Albinism
  • 12:00Conclusion

Summary

Automatic Translation

This manuscript describes deterministic and probabilistic algorithms for white matter (WM) reconstruction, used to examine differences in optic radiation (OR) connectivity between albinism and controls. Although probabilistic tractography follows the true course of nerve fibers more closely, deterministic tractography was run to compare the reliability and reproducibility of both techniques.

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