Waiting
Procesando inicio de sesión ...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Immunology and Infection / Isolation and Transplantation of Different Aged…
JoVE Journal
Immunology and Infection

Se requiere una suscripción a JoVE para ver este contenido.

JoVE Journal Immunology and Infection
Isolation and Transplantation of Different Aged Murine Thymic Grafts.
Retroviral Transduction of T-cell Receptors in Mouse T-cells
Journal (Immunology and Infection)
Retroviral Transduction of T-cell Receptors in Mouse T-cells
Multiplex Cytokine Profiling of Stimulated Mouse Splenocytes Using a Cytometric Bead-based Immunoassay Platform
Journal (Immunology and Infection)
Multiplex Cytokine Profiling of Stimulated Mouse Splenocytes Using a Cytometric Bead-based Immunoassay Platform
 

Isolation and Transplantation of Different Aged Murine Thymic Grafts.

Article DOI: 10.3791/52709-v • 05:47 min • May 13th, 2015
May 13th, 2015 •
*1, *1, 1, 1
1Department of Microbiology and Immunology, University of North Carolina at Chapel Hill
* These authors contributed equally

Capítulos

Resumen
Automatic Translation

This report provides a detailed description of transplanting murine thymi from different aged donor mice under the kidney capsule of immunodeficient mouse recipients. The goal of this approach is to model T cell development and thymic selection events in vivo.

Tags

Isolation Transplantation Aged Murine Thymic Grafts Thymic Selection T Cells Self Antigens Foreign Antigens Immunodeficient Scid Recipients Reconstitution Thymus Graft Thymocytes Mature T Cells Age-dependent Thymic Events Pathologies Aberrant Thymic Function Homeostasis
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter