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Co-cultuur van glutamaterge neuronen en pediatrische hoogwaardige glioomcellen in microfluïdische apparaten om elektrische interacties te beoordelen
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Co-cultuur van glutamaterge neuronen en pediatrische hoogwaardige glioomcellen in microfluïdische apparaten om elektrische interacties te beoordelen

Article DOI: 10.3791/62748-v • 07:39 min • November 17th, 2021
November 17th, 2021 •
1, 2, 2, 2, 2, 2, 2, 2, 2, 2, 1, 1, 1,3, 1, 1,4
1Team Tumoral signaling and therapeutic targets, UMR CNRS 7021 - Laboratory of Bioimaging and Pathologies, 2NETRI, 3Centre de Ressources Biologiques, Pathology department, University Hospital of Strasbourg, 4Pediatric Oncohematology unit, University Hospital of Strasbourg

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Recente werken onthullen de neuronale impact op hoogwaardige pediatrische glioomcellen (pHGG) en hun wederzijdse interacties. Het huidige werk toont de ontwikkeling van een in vitro model dat pHGG-cellen en glutamaterge neuronen co-cultiveert en hun elektrofysiologische interacties registreerde om die interactiviteiten na te bootsen.

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