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Journal / Bioengineering / 狂犬病抗原を封入した拍動性高分子微粒子の作製…
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Bioengineering

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JoVE Journal Bioengineering
狂犬病抗原を封入した拍動性高分子微粒子の作製
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狂犬病抗原を封入した拍動性高分子微粒子の作製

Article DOI: 10.3791/65147-v • 07:44 min • May 12th, 2023
May 12th, 2023 •
*1, *2, 1, 3, 2, 1, 2, 1,4
1Department of Bioengineering, Rice University, 2Particles for Humanity, 3IMPACT Technology Development, 4Department of Chemistry, Rice University
* These authors contributed equally

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この方法は、狂犬病抗原を、所定の遅延後に拍動放出を可能にする構造的および材料的特性を有する生分解性ポリマー微粒子に封入することを記載する。粒子コアから回収された抗原の酵素結合免疫吸着アッセイ(ELISA)評価では、粒子作製を通じて無傷の三量体狂犬病ウイルス糖タンパク質の存在が確認されます。

Tags

空の値、問題195、制御放出、拍動性送達、ポリ(乳酸-co-グリコール酸)、狂犬病、ELISA、曝露後予防、ワクチン接種
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