Colin G. Nichols Department of Cell Biology and Physiology and Center for the Investigation of Membrane Excitability Diseases Washington University in St. Louis Biography Publications Institution JoVE Articles Colin G. Nichols has not added a biography. If you are Colin G. Nichols and would like to personalize this page please email our Author Liaison for assistance. Publications ATP-sensitive Potassium Channels in Zebrafish Cardiac and Vascular Smooth Muscle The Journal of Physiology. 01, 2022 | Pubmed ID: 34820842 Beta-cell Excitability and Excitability-driven Diabetes in Adult Zebrafish Islets Physiological Reports. 06, 2019 | Pubmed ID: 31161721 Potassium Channel Selectivity Filter Dynamics Revealed by Single-molecule FRET Nature Chemical Biology. 04, 2019 | Pubmed ID: 30833778 Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension Circulation. Genomic and Precision Medicine. 10, 2018 | Pubmed ID: 30354297 Polyamines and Potassium Channels: A 25-year Romance The Journal of Biological Chemistry. 11, 2018 | Pubmed ID: 30333230 Contribution of Systemic Inflammation to Permanence of K-induced Neonatal Diabetes in Mice American Journal of Physiology. Endocrinology and Metabolism. 12, 2018 | Pubmed ID: 30226997 Cantu Syndrome-associated SUR2 (ABCC9) Mutations in Distinct Structural Domains Result in K Channel Gain-of-function by Differential Mechanisms The Journal of Biological Chemistry. 02, 2018 | Pubmed ID: 29275331 Studying Structural Dynamics of Potassium Channels by Single-Molecule FRET Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29058191 Conserved Functional Consequences of Disease-associated Mutations in the Slide Helix of Kir6.1 and Kir6.2 Subunits of the ATP-sensitive Potassium Channel The Journal of Biological Chemistry. 10, 2017 | Pubmed ID: 28842488 Transient Notch Activation Induces Long-Term Gene Expression Changes Leading to Sick Sinus Syndrome in Mice Circulation Research. Aug, 2017 | Pubmed ID: 28674041 Conformational Changes at Cytoplasmic Intersubunit Interactions Control Kir Channel Gating The Journal of Biological Chemistry. 06, 2017 | Pubmed ID: 28446610 Control of Kir Channel Gating by Cytoplasmic Domain Interface Interactions The Journal of General Physiology. May, 2017 | Pubmed ID: 28389584 Expression and Function of ATP-dependent Potassium Channels in Zebrafish Islet β-cells Royal Society Open Science. Feb, 2017 | Pubmed ID: 28386438 Structural Basis of Control of Inward Rectifier Kir2 Channel Gating by Bulk Anionic Phospholipids The Journal of General Physiology. 09, 2016 | Pubmed ID: 27527100 Adenosine Triphosphate-Sensitive Potassium Currents in Heart Disease and Cardioprotection Cardiac Electrophysiology Clinics. 06, 2016 | Pubmed ID: 27261824 K(ATP) Channel Gain-of-function Leads to Increased Myocardial L-type Ca(2+) Current and Contractility in Cantu Syndrome Proceedings of the National Academy of Sciences of the United States of America. 06, 2016 | Pubmed ID: 27247394 Differential Mechanisms of Cantú Syndrome-associated Gain of Function Mutations in the ABCC9 (SUR2) Subunit of the KATP Channel The Journal of General Physiology. Dec, 2015 | Pubmed ID: 26621776 ABCC8 R1420H Loss-of-Function Variant in a Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of Type 2 Diabetes Diabetes. Dec, 2015 | Pubmed ID: 26246406 Electrophysiologic Consequences of KATP Gain of Function in the Heart: Conduction Abnormalities in Cantu Syndrome Heart Rhythm. Nov, 2015 | Pubmed ID: 26142302 Modeling K,ATP--dependent Excitability in Pancreatic Islets Biophysical Journal. Nov, 2014 | Pubmed ID: 25418087 Energetics and Location of Phosphoinositide Binding in Human Kir2.1 Channels The Journal of Biological Chemistry. Jun, 2013 | Pubmed ID: 23564459 KATP Channels and Cardiovascular Disease: Suddenly a Syndrome Circulation Research. Mar, 2013 | Pubmed ID: 23538276 The Diabetic β-cell: Hyperstimulated Vs. Hyperexcited Diabetes, Obesity & Metabolism. Oct, 2012 | Pubmed ID: 22928573 Dual-mode Phospholipid Regulation of Human Inward Rectifying Potassium Channels Biophysical Journal. Feb, 2011 | Pubmed ID: 21281576 Beta-cell Hyperexcitability: from Hyperinsulinism to Diabetes Diabetes, Obesity & Metabolism. Nov, 2007 | Pubmed ID: 17919182 从成年、幼年、幼虫和胚胎斑马鱼中分离心脏和血管平滑肌细胞以进行电生理研究 Soma S. Singareddy1, Conor McClenaghan1, Helen I. Roessler2, Robert Tryon1, Colin G. Nichols1 1Department of Cell Biology and Physiology and Center for the Investigation of Membrane Excitability Diseases, Washington University in St. Louis, 2Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University JoVE 63225 Biologie
从成年、幼年、幼虫和胚胎斑马鱼中分离心脏和血管平滑肌细胞以进行电生理研究 Soma S. Singareddy1, Conor McClenaghan1, Helen I. Roessler2, Robert Tryon1, Colin G. Nichols1 1Department of Cell Biology and Physiology and Center for the Investigation of Membrane Excitability Diseases, Washington University in St. Louis, 2Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University JoVE 63225 Biologie
